Results 31 to 40 of about 1,531,774 (311)

Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4

Skeletal Muscle, 2016
Background Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handling proteins, notably TDP-43 and FUS,
Sachiko Homma, Mary Lou Beermann, Bryant Yu, Frederick M. Boyce, Jeffrey Boone Miller   +4 more
doaj   +1 more source

Bioelectrical impedance vectors analysis (BIVA) in older adults according to level of physical activity and muscle strength: a comparison of classic and specific approaches

Frontiers in Aging
IndroductionBioelectrical Impedance Analysis (BIA) is a widely used method to assess body composition. Traditional BIA models use predictive equations without considering individual characteristics such as age, sex, and activity level.
Ismael Figueiredo Rabelo, Shannon Farrell, Kieran F. Reid, Vanessa Ribeiro Dos Santos, Melissa Antunes, Vitor Cabrera Batista, Andreia Bauermann-Vieira, Luís Alberto Gobbo   +7 more
doaj   +1 more source

Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells

Skeletal Muscle, 2019
Background Osteopontin is secreted by skeletal muscle myoblasts and macrophages, and its expression is upregulated in muscle following injury. Osteopontin is present in many different structural forms, which vary in their expression patterns and effects ...
Dimuthu K. Wasgewatte Wijesinghe, Eleanor J. Mackie, Charles N. Pagel   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Nicotinamide phosphoribosyltransferase (Nampt) in Lateral Hypothalamus Maintains Skeletal Muscle Functions Through Lactate‐Mediated Calcium Signalling in Male Mice

Journal of Cachexia, Sarcopenia and Muscle
Background Sarcopenia has become an urgent socioeconomic problem in rapidly aging societies. The pathogenesis of age‐associated sarcopenia is not fully understood and no effective therapeutic strategies have been developed to date.
Takahiro Eguchi, Keiko Kabetani, Naoki Ito   +2 more
doaj   +1 more source

Diversification of the muscle proteome through alternative splicing

Skeletal Muscle, 2018
Background Skeletal muscles express a highly specialized proteome that allows the metabolism of energy sources to mediate myofiber contraction. This muscle-specific proteome is partially derived through the muscle-specific transcription of a subset of ...
Kiran Nakka, Claudia Ghigna, Davide Gabellini, F. Jeffrey Dilworth   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Nitric oxide synthase in skeletal muscle fibres of patients with type 2 diabetes [PDF]

, 2012
Muscle-derived nitric oxide (NO) mediates fundamental physiological actions on skeletal muscle including glucose uptake into muscle cells. Recently, we have shown that the altered glucose metabolism in skeletal muscle of patients with type 2 diabetes ...
Karla Punkt, Volker Adams, Katharina Kandt, Matthias Blueher, Andreas Oberbach, Igor Buchwalow   +5 more
core  

Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice [PDF]

, 2014
Pharmacokinetics and effects on skeletal muscle and physical performance of oral acetylcarnitine and propionylcarnitine are not well characterized. We therefore investigated the influence of oral acetylcarnitine, propionylcarnitine, and carnitine on body
Morand, Réjane, Handschin, Christoph, Hench, Jürgen, Felser, Andrea, Krähenbühl, Stephan, Bouitbir, Jamal, Frank, Stephan, Frank S, Krähenbühl S, Felser A, Hench J, Morand R, Bouitbir J, Handschin C   +13 more
core   +1 more source

Weightlifting outperforms voluntary wheel running for improving adiposity and insulin sensitivity in obese mice

Journal of Sport and Health Science
Background: Exercise is an effective intervention for obesity and type 2 diabetes, with significant physiological benefits over pharmacological interventions.
Robert J. Shute, Ryan N. Montalvo, Wenqing Shen, Yuntian Guan, Qing Yu, Mei Zhang, Zhen Yan   +6 more
doaj   +1 more source