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Regulation of Skeletal Muscle Function by Amino Acids
Amino acids are components of proteins that also exist free-form in the body; their functions can be divided into (1) nutritional, (2) sensory, and (3) biological regulatory roles.
Yasutomi Kamei+4 more
semanticscholar +1 more source
A bioengineered skeletal muscle construct that mimics structural and functional characteristics of native skeletal muscle is a promising therapeutic option to treat extensive muscle defect injuries.
J. Kim+6 more
semanticscholar +1 more source
In the beginning of the last century, muscle proteins were viewed as static structural molecules not capable of being utilized by other tissues or organs. This concept was accepted until the 30s, where Rudolf Schoenheimer presented strong evidences about the “Dynamic State of Body Constituents,” which means that skeletal muscle is not only capable of ...
Jacob M. Wilson+3 more
openaire +4 more sources
Skeletal Myogenic Progenitors Originating from Embryonic Dorsal Aorta Coexpress Endothelial and Myogenic Markers and Contribute to Postnatal Muscle Growth and Regeneration [PDF]
Skeletal muscle in vertebrates is derived from somites, epithelial structures of the paraxial mesoderm, yet many unrelated reports describe the occasional appearance of myogenic cells from tissues of nonsomite origin, suggesting either ...
Berghella, Libera+7 more
core +2 more sources
Autophagy in skeletal muscle [PDF]
Muscle mass represents 40–50% of the human body and, in mammals, is one of the most important sites for the control of metabolism. Moreover, during catabolic conditions, muscle proteins are mobilized to sustain gluconeogenesis in the liver and to provide alternative energy substrates for organs.
openaire +4 more sources
Skeletal Muscle Mitochondria and Aging: A Review
Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines in skeletal muscle mitochondria are thought to play a primary role in this process.
Courtney M. Peterson+2 more
doaj +1 more source
Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco+6 more
core +1 more source
Targeting healthspan to optimally combat non-communicable disease in an aging world
Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
doaj +1 more source
Background In Duchenne muscular dystrophy (DMD), DYSTROPHIN deficiency exposes myofibers to repeated cycles of contraction/degeneration, ultimately leading to muscle loss and replacement by fibrotic tissue.
Luca Caputo+6 more
doaj +1 more source
Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma [PDF]
BACKGROUND: Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells.
Bisognin, Andrea+2 more
core +2 more sources