Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease [PDF]
, 2017 Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia, promotes the formation of atheromatous plaques in large vessels of the cardiovascular system.
Matsakas, Antonios, Sfyri, Peggy
core +1 more source
Regulation of Skeletal Muscle Function by Amino Acids
Nutrients, 2020 Amino acids are components of proteins that also exist free-form in the body; their functions can be divided into (1) nutritional, (2) sensory, and (3) biological regulatory roles.
Yasutomi Kamei +4 more
semanticscholar +1 more source
Mechanism of increased risk of insulin resistance in aging skeletal muscle
Diabetology & Metabolic Syndrome, 2020 As age increases, the risk of developing type 2 diabetes increases, which is associated with senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction, intramyocellular lipid accumulation, increased inflammation ...
J. Shou, Pei-jie Chen, W. Xiao
semanticscholar +1 more source
Skeletal Muscle Mitochondria and Aging: A Review
Journal of Aging Research, 2012 Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines in skeletal muscle mitochondria are thought to play a primary role in this process.
Courtney M. Peterson +2 more
doaj +1 more source
Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells [PDF]
, 2017 Testosterone by promoting different metabolic pathways contributes to short-term homeostasis of skeletal muscle, the largest insulin-sensitive tissue and the primary site for insulin-stimulated glucose utilization.
Antinozzi, Cristina +8 more
core +2 more sources
Targeting healthspan to optimally combat non-communicable disease in an aging world
Sports Medicine and Health Science, 2019 Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
doaj +1 more source
Skeletal Myogenic Progenitors Originating from Embryonic Dorsal Aorta Coexpress Endothelial and Myogenic Markers and Contribute to Postnatal Muscle Growth and Regeneration [PDF]
, 1999 Skeletal muscle in vertebrates is derived from somites, epithelial structures of the paraxial mesoderm, yet many unrelated reports describe the occasional appearance of myogenic cells from tissues of nonsomite origin, suggesting either ...
Berghella, Libera +7 more
core +2 more sources
Human cachexia induces changes in mitochondria, autophagy and apoptosis in the skeletal muscle [PDF]
, 2019 Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life.
Alcantara, P. S. +9 more
core +1 more source
Skeletal Muscle Health and Cognitive Function: A Narrative Review
International Journal of Molecular Sciences, 2020 Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and reduced neurological drive. Cognitive decline refers to diminished or
Sophia X. Sui +4 more
semanticscholar +1 more source
Prions in skeletal muscle [PDF]
Proceedings of the National Academy of Sciences, 2002 Considerable evidence argues that consumption of beef products from cattle infected with bovine spongiform encephalopathy (BSE) prions causes new variant Creutzfeldt–Jakob disease. In an effort to prevent new variant Creutzfeldt–Jakob disease, certain “specified offals,” including neural and lymphatic tissues, thought to contain high ...
BOSQUE PJ +6 more
openaire +5 more sources