Results 251 to 260 of about 352,666 (292)

Lysosomes and disuse atrophy of skeletal muscle

Archives of Biochemistry and Biophysics, 1971
The specific activities of the acid hydrolases β-glucosidase, β-galactosidase, β-N-acetylhexosaminidase, arylsulfatase, and acid phosphatase have been measured during the time course of disuse atrophy of rat gastrocnemius muscles. These enzymes are considered to be lysosomal in origin.
S R, Max, R F, Mayer, L, Vogelsang
openaire   +2 more sources

Regrowth of Skeletal Muscle Atrophied from Inactivity

Medicine & Science in Sports & Exercise, 2004
The current state of knowledge regarding regrowth of skeletal muscle after inactivity-induced atrophy is reviewed. Muscle regrowth is incomplete after hindlimb suspension in juvenile rats and after limb immobilization in old animals. The process of regrowth from immobilization-induced atrophy likely involves the reversal of directional changes in ...
Shuichi, Machida, Frank W, Booth
openaire   +2 more sources

Skeletal muscle hypertrophy and atrophy signaling pathways

The International Journal of Biochemistry & Cell Biology, 2005
Skeletal muscle hypertrophy is defined as an increase in muscle mass, which in the adult animal comes as a result of an increase in the size, as opposed to the number, of pre-existing skeletal muscle fibers. The protein growth factor insulin-like growth factor 1 (IGF-1) has been demonstrated to be sufficient to induce skeletal muscle hypertrophy.
openaire   +2 more sources

Angiotensin II: Role in Skeletal Muscle Atrophy

Current Protein & Peptide Science, 2012
Skeletal muscle, the main protein reservoir in the body, is a tissue that exhibits high plasticity when exposed to changes. Muscle proteins can be mobilized into free amino acids when skeletal muscle wasting occurs, a process called skeletal muscle atrophy.
Claudio, Cabello-Verrugio, Gonzalo, Córdova, José Diego, Salas   +2 more
openaire   +2 more sources

Skeletal muscle atrophy: disease-induced mechanisms may mask disuse atrophy

Journal of Muscle Research and Cell Motility, 2015
Disuse atrophy is the loss of skeletal muscle mass due to inactivity or lower than 'normal' use. It is not only a furtive component of the 'modern' sedentary lifestyle but also a part of numerous pathologies, where muscle loss is linked to disease specific and/or other toxicity factors, eventually leading to wasting (cachexia).
Malavaki, C. J., Sakkas, Giorgos K., Mitrou, G. I., Kalyva, A., Stefanidis, I., Myburgh, K. H., Karatzaferi, Christina   +6 more
openaire   +3 more sources

Progressive Atrophy of Skeletal Muscles

Postgraduate Medicine, 1967
The “motor unit” concept is delineated and a classification of atrophies is presented. The four main categories are composed of disease states associated with (1) proximal symmetric, (2) distal symmetric, (3) diffuse bilateral and (4) restricted atrophies of skeletal muscles.
openaire   +2 more sources

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Nature Cell Biology, 2001
S. Bodine, T. Stitt, Michael Gonzalez, W. O. Kline, Gretchen L. Stover, Roy Bauerlein, Elizabeth Zlotchenko, A. Scrimgeour, J. Lawrence, D. Glass, G. Yancopoulos   +10 more
semanticscholar   +1 more source

Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes

Nature Metabolism, 2021
J. Okun, Patricia M. Rusu, Andrea Y. Chan, Yuqin Wu, Y. Yap, Thomas Sharkie, J. Schumacher, Kathrin V. Schmidt, K. Roberts-Thomson, Ryan D. Russell, Annika Zota, S. Hille, A. Jungmann, Ludovico Maggi, Y. Lee, M. Blüher, S. Herzig, M. Keske, M. Heikenwalder, O. Müller, A. Rose   +20 more
semanticscholar   +1 more source

Disuse Atrophy of Skeletal Muscle

Exercise and Sport Sciences Reviews, 1988
X J, Musacchia, J M, Steffen, R D, Fell
openaire   +2 more sources

Control of satellite cell function in muscle regeneration and its disruption in ageing

Nature Reviews Molecular Cell Biology, 2021
Pedro Sousa-Victor, Pura Muñoz-Cánoves
exaly