Results 221 to 230 of about 64,656 (260)
Some of the next articles are maybe not open access.
Skeletal muscle regeneration and the mitotic clock
Experimental Gerontology, 2000Regeneration of muscle fibers following damage requires activation of quiescent satellite cells, their proliferation and finally their differentiation and fusion into multinucleated myotubes, which after maturation will replace the damaged fiber.
V, Renault +8 more
openaire +2 more sources
Regeneration versus fibrosis in skeletal muscle
Current Opinion in Rheumatology, 2011This review evaluates recently published literature examining various muscle tissue cells and their modulators that determine whether injured skeletal muscle will fully regenerate or become fibrotic.Muscle regeneration is a complex process involving several interacting cell types. Macrophages initiate a cytokine response to injury that both directs the
Adam L, Moyer, Kathryn R, Wagner
openaire +2 more sources
Skeletal Muscle Stem Cells for Muscle Regeneration
2014Adult skeletal muscle possesses remarkable regenerative capacity. Muscle regeneration is mediated by a rare population of muscle stem cells that reside between the basal lamina and sarcolemma of muscle fibers. Due to their anatomical location, muscle stem cells have been coined satellite cells.
Johnny, Kim, Thomas, Braun
openaire +2 more sources
Pattern of skeletal muscle regeneration after reautotransplantation of regenerated muscle
Development, 1986ABSTRACT Autotransplantation of rat extensor digitorum longus muscle results in initial myofibre degeneration and subsequent regeneration from precursor myosatellite cells. To determine what effect a reinjury would have on the regenerative response, in the present.study, once transplanted and regenerated muscles were reinjured by ...
openaire +2 more sources
Skeletal muscle regeneration in young rats
American Journal of Anatomy, 1972AbstractThe source of myotube nuclei in regeneration of skeletal muscle in young rats was studied by comparing frequencies of labeled nuclei in two experiments. In a single injury experiment, multiple injections of thymidine‐H3 were given during a three day period, skeletal muscle was injured 12 days later and the rats were killed four days after ...
openaire +2 more sources
Effects of aging on skeletal muscle regeneration
Journal of the Neurological Sciences, 1988Bupivacaine was injected into the anterior tibial muscles of 2-year-old rats. The induced degeneration - regeneration was slow, taking 3 weeks to completion (1 week in young rats). The reconstituted muscle showed small fiber size, an increased number of internal nuclei and longitudinal splitting.
openaire +2 more sources
Fenestrations in regenerating skeletal muscle capillaries
American Journal of Anatomy, 1977AbstractA new observation of fenestrae with diaphragms in the endothelial wall of regenerating skeletal muscle capillaries is described in seven‐day‐old wounds of the cremaster muscle of adult male guinea pigs. The fenestrations were 44 nm in diameter and contained diaphragms with a central dense structure.
R V, McKinney, B B, Singh, P D, Brewer
openaire +2 more sources
Satellite Cells and Skeletal Muscle Regeneration
Comprehensive Physiology, 2015ABSTRACT Skeletal muscles are essential for vital functions such as movement, postural support, breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic multinucleated fibers. The life‐long maintenance of muscle tissue is mediated by satellite cells, lying in close proximity to the ...
Dumont, Nicolas A. +3 more
openaire +3 more sources
Cellular Biomechanics in Skeletal Muscle Regeneration
2018Satellite cells, adult stem cells in skeletal muscle tissue, reside within a mechanically dynamic three-dimensional microenvironment. With each contraction-relaxation cycle, a satellite cell is expected to experience tensile, shear, and compressive stresses, and through cell-extracellular matrix interactions, also gauge the stiffness of the niche.
Edward W, Li +2 more
openaire +2 more sources
Metabolic studies of skeletal muscle regeneration
Experimental Neurology, 1974Metabolic studies were carried out on regenerating skeletal muscle in the rat following intramuscular injection of the myotoxic agent Marcaine plus hyaluronidase or after mincing and autoimplantation. Both after mincing and following injection of Marcaine, the ability to oxidize glucose-6-14C and palmitate-1-14C was lost, while the oxidation of glucose-
D H, Rifenberick, C L, Koski, S R, Max
openaire +2 more sources