Orally Administered Edible Snail Extract Powder Enhances Skin Hydration via Hyaluronic Acid Synthesis and Barrier Gene Modulation in SKH-1 Hairless Mice. [PDF]
Food Sci NutrImmunohistochemical staining of dorsal skin tissues for HAS2, HYAL1, and TGF‐β1. Oral administration of SEP increased the expression of HAS2 and TGF‐β1 in a dose‐dependent manner, while reducing HYAL1 expression. These findings indicate that SEP promotes hyaluronic acid synthesis and extracellular matrix remodeling. The results support the moisturizing
Lee C, Baek S, Lim W, Lim TG.
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Chemoprotective Effects of Dietary Grape Powder on UVB Radiation-Mediated Skin Carcinogenesis in SKH-1 Hairless Mice. [PDF]
J Invest Dermatol, 2019 Skin cancer is the most frequently diagnosed cancer in the United States, and solar UVR is an established causative factor for approximately 90% of these cases. Despite efforts aimed at UV protection, including use of sunscreen and clothing, annual cases of skin cancer continue to rise.
Singh CK +7 more
europepmc +4 more sources
Oral Intake of Lactobacillus helveticus NS8 Alleviates Ovalbumin-Induced Atopic Dermatitis in SKH-1 Hairless Mice. [PDF]
Indian J Microbiol, 2018 Atopic dermatitis (AD) is the most common chronic inflammatory skin disease and is driven by strong type 2 immune responses. Lactobacillus helveticus NS8 (NS8), a probiotic strain isolated from Mongolian koumiss, has anti-inflammatory activities. Here, we evaluated the therapeutic potential of NS8 on AD-like skin lesions by using SKH-1 hairless mice ...
Rong J, Liu S, Hu C, Jin F, Wang L.
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Photoprotection of Buddleja cordata extract against UVB-induced skin damage in SKH-1 hairless mice. [PDF]
BMC Complement Altern Med, 2014 En los últimos años, ha habido un considerable interés en el uso de agentes botánicos para prevenir el daño cutáneo resultante de la radiación solar UV. Buddleja cordata es una planta que se conoce como "tepozan". Algunas personas en México utilizan las hojas de esta planta para tratar tumores, abscesos, llagas y quemaduras.
Avila Acevedo JG +8 more
europepmc +4 more sources
Endogenous Retinoic Acid Required to Maintain the Epidermis Following Ultraviolet Light Exposure in SKH-1 Hairless Mice. [PDF]
Photochem Photobiol, 2015 AbstractUltraviolet light B (UVB) exposure induces cutaneous squamous cell carcinoma (cSCC), one of the most prevalent human cancers. Reoccurrence of cSCC in high‐risk patients is prevented by oral retinoids. But oral retinoid treatment causes significant side effects; and patients develop retinoid resistance.
Gressel KL +4 more
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Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice. [PDF]
PLoS ONE, 2013 A paucity of clinically applicable biomarkers to screen therapies in laboratory is a limitation in the development of countermeasures against cutaneous injuries by chemical weapon, sulfur mustard (SM), and its analog nitrogen mustard (NM).
Neera Tewari-Singh +4 more
doaj +3 more sources
Establishment of a BALB/c Mouse Model for Photoaged Skin: Insights into UV-Induced Dermatological Changes. [PDF]
Skin Res TechnolABSTRACT Background Photoaging, primarily induced by prolonged ultraviolet (UV) radiation exposure, significantly alters skin structure and function, necessitating models for deeper understanding and intervention development. This study aims to establish a BALB/c mouse model for investigating photoaging, leveraging their haired skin and genetic ...
Huynh CB, Vu NB, The Van T, Van Pham P.
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Effects of Egg Shell Membrane Hydrolysates on UVB-radiation-induced Wrinkle Formation in SKH-1 Hairless Mice. [PDF]
Korean J Food Sci Anim Resour, 2015 This study was conducted to examine the effect of egg shell membrane hydrolysates (ESMH) on wrinkle, UV, and moisture protection for cosmetic use. ESMH were fragmented as whole ESMH (before fractioning), Fraction I (> 10 kDa), Fraction II (3-10 kDa), and Fraction III (< 3 kDa).
Yoo JH, Kim JK, Yang HJ, Park KM.
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Role of p38 MAPK in UVB-Induced Inflammatory Responses in the Skin of SKH-1 Hairless Mice [PDF]
Journal of Investigative Dermatology, 2005 The p38 mitogen-activated protein kinase (MAPK) signaling pathway is activated by numerous inflammatory mediators and environmental stresses. We assessed the effects of ultraviolet B (UVB) on the p38 MAPK pathway and determined whether cyclooxygenase (COX)-2 expression is downstream of this kinase in the skin of UVB-irradiated SKH-1 mice.
Kim Mcclure +2 more
exaly +3 more sources
Oral Administration of Edible Snail Extract Powder Prevents UVB-Induced Skin Damage. [PDF]
Food Sci NutrOral administration of edible snail extract powder (SEP) significantly protected against UVB‐induced skin damage in SKH‐1 hairless mice. SEP improved skin hydration, reduced wrinkle formation, and restored the expression of key genes related to hyaluronic acid synthesis, collagen production, and antioxidant defense. These findings suggest SEP may serve
Koo J, Cho S, Lim W, Lim TG.
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