Results 31 to 40 of about 775 (254)

The effect of gabion steps on the hydraulic jump characteristics downstream of stepped spillways

open access: yesWater Science
Gabion steps on stepped spillways can be a suitable alternative to solid impermeable steps due to their economic advantages, ease of implementation, stability through water pressure reduction, and energy dissipation.
Rasoul Daneshfaraz   +3 more
doaj   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

open access: yesAdvanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima   +15 more
wiley   +1 more source

Measurements of Wake Concentration from the Continuous Release of a Dense Fluid Upstream of a Cubic Obstacle

open access: yesFluids
Results are presented from a series of small-scale laboratory experiments designed to model dense gas dispersion around an isolated cuboid building. Experiments were conducted for a broad range of flow Richardson numbers and source discharge rates, and ...
Romana Akhter, Nigel B. Kaye
doaj   +1 more source

Multimodal Locomotion in Insect‐Inspired Microrobots: A Review of Strategies for Aerial, Surface, Aquatic, and Interfacial Motion

open access: yesAdvanced Robotics Research, EarlyView.
This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska   +2 more
wiley   +1 more source

Self-Sovereign Identity Empowered Automated Teller Machines

open access: yesIEEE Access
To withdraw cash or make a payment, customers can use their bank’s interactive Automated Teller Machines (ATMs), debit card, or credit card systems. With these advances, customers no longer have to physically visit a bank to withdraw funds or make
Fairuz Rahaman Chowdhury   +5 more
doaj   +1 more source

Effects of Turbulence Manipulation in Skimming Flows: An Experimental Study [PDF]

open access: yes, 2004
Current expertise in air-water flow properties in turbulent flows is limited to low to moderate Reynolds numbers and a few types of surfaces (roughness).
Chanson, Hubert   +3 more
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Experimental Investigations of Air Entrainment in Transition and Skimming Flows down a Stepped Chute: Application to Embankment Overflow Stepped Spillways [PDF]

open access: yes, 2001
Stepped spillways have been used for about 3,500 years. The last few decades have seen the development of new construction materials, design techniques and applications : e.g., embankment overtopping protection systems.
Chanson, H., Toombes, L.
core  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

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