Effect of Cosmetics Use on the In Vitro Skin Absorption of a Biocide, 1,2-Benzisothiazolin-3-one [PDF]
1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure, and
Yoonjung Huh+3 more
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Is the Skin Absorption of Hydrocortisone Modified by the Variability in Dosing Topical Products? [PDF]
Fingertip units have been proposed as a tool to standardize topical therapy with semisolid formulations. However, no studies to date have characterized the variability in dosing by patients using this concept and whether this variability ultimately ...
Daniel A. Paterson+4 more
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Skin Absorption of Solvent Mixtures. Effect of Vehicles on Skin Absorption of Toluene.
The skin absorption rates of toluene in various solvent mixtures were investigated in mice. The skin absorption rate of toluene in toluene/methanol mixtures exhibited a parabolic relationship to the mixed ratio. The maximum rate was obtained at a mixed ratio of 50% (V/V).
Hiroshi Tsuruta
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A Study of the Skin Absorption of Ethylbenzene in Man [PDF]
The absorption of ethylbenzene through the skin of the hand and the forearm in men was investigated experimentally. Both the absorption of liquid ethylbenzene and the absorption from aqueous solutions were studied. The rate of absorption of liquid ethylbenzene was 22 to 33 mg./cm. 2 /hr, and the rates from aqueous solutions were 118 and 215 μg./cm.
Halina Tyras, Tadeusz Dutkiewicz
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Solute–Vehicle–Skin Interactions and Their Contribution to Pharmacokinetics of Skin Delivery [PDF]
Human skin provides an effective route of delivery for selected drugs. Topical penetration of molecules is largely attributed to passive diffusion, and the degree of penetration can be represented by in silico, in vitro, and ex vivo models.
Pronalis Tapfumaneyi+6 more
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Evaluation of skin absorption of drugs from topical and transdermal formulations [PDF]
The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs.
André Luís Morais Ruela+4 more
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Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases [PDF]
There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals.
Angerer Jürgen+3 more
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Transcutaneous Absorption of Iodine in Pediatric Cardiac Surgery Following the Topical Use of Povidone Iodine [PDF]
BACKGROUND: There is still a controversy about the best method for preoperative skin preparation (skin cleaning).The main antiseptic solution used in the cardiac surgery room is Povidone Iodine (PI), which is used to prepare the area to be operated on ...
Hamid Ghaderi+9 more
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Photodynamic therapy (PDT) using methylene blue (MB) as a photosensitizer has emerged as an alternative treatment for skin cancers, such as squamous cell carcinoma (SCC).
Thayane Soares Lima+4 more
doaj +1 more source
Transdermal drug administration is an elegant method to overcome various side effects of oral or parenteral drug administration. Nevertheless, due to an effective skin barrier, which is provided by the stratum corneum, transdermal drug delivery is ...
Anna-Lena Elksnat+4 more
doaj +1 more source