Results 1 to 10 of about 187,636 (307)

Effect of Cosmetics Use on the In Vitro Skin Absorption of a Biocide, 1,2-Benzisothiazolin-3-one [PDF]

open access: yesToxics, 2022
1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure, and
Yoonjung Huh   +3 more
doaj   +2 more sources

Is the Skin Absorption of Hydrocortisone Modified by the Variability in Dosing Topical Products? [PDF]

open access: yesPharmaceutics, 2018
Fingertip units have been proposed as a tool to standardize topical therapy with semisolid formulations. However, no studies to date have characterized the variability in dosing by patients using this concept and whether this variability ultimately ...
Daniel A. Paterson   +4 more
doaj   +2 more sources

Skin Absorption of Solvent Mixtures. Effect of Vehicles on Skin Absorption of Toluene.

open access: bronzeINDUSTRIAL HEALTH, 1996
The skin absorption rates of toluene in various solvent mixtures were investigated in mice. The skin absorption rate of toluene in toluene/methanol mixtures exhibited a parabolic relationship to the mixed ratio. The maximum rate was obtained at a mixed ratio of 50% (V/V).
Hiroshi Tsuruta
openaire   +5 more sources

A Study of the Skin Absorption of Ethylbenzene in Man [PDF]

open access: bronzeOccupational and Environmental Medicine, 1967
The absorption of ethylbenzene through the skin of the hand and the forearm in men was investigated experimentally. Both the absorption of liquid ethylbenzene and the absorption from aqueous solutions were studied. The rate of absorption of liquid ethylbenzene was 22 to 33 mg./cm. 2 /hr, and the rates from aqueous solutions were 118 and 215 μg./cm.
Halina Tyras, Tadeusz Dutkiewicz
openaire   +4 more sources

Solute–Vehicle–Skin Interactions and Their Contribution to Pharmacokinetics of Skin Delivery [PDF]

open access: yesPharmaceutics
Human skin provides an effective route of delivery for selected drugs. Topical penetration of molecules is largely attributed to passive diffusion, and the degree of penetration can be represented by in silico, in vitro, and ex vivo models.
Pronalis Tapfumaneyi   +6 more
doaj   +2 more sources

Evaluation of skin absorption of drugs from topical and transdermal formulations [PDF]

open access: diamondBrazilian Journal of Pharmaceutical Sciences, 2016
The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs.
André Luís Morais Ruela   +4 more
doaj   +2 more sources

Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases [PDF]

open access: goldJournal of Occupational Medicine and Toxicology, 2006
There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals.
Angerer Jürgen   +3 more
doaj   +2 more sources

Transcutaneous Absorption of Iodine in Pediatric Cardiac Surgery Following the Topical Use of Povidone Iodine [PDF]

open access: yesARYA Atherosclerosis, 2022
BACKGROUND: There is still a controversy about the best method for preoperative skin preparation (skin cleaning).The main antiseptic solution used in the cardiac surgery room is Povidone Iodine (PI), which is used to prepare the area to be operated on ...
Hamid Ghaderi   +9 more
doaj   +1 more source

Nanoencapsulation of Methylene-Blue for Enhanced Skin Cancer Cell Phototoxicity and Cutaneous Penetration in Association with Sonophoresis

open access: yesPharmaceutics, 2023
Photodynamic therapy (PDT) using methylene blue (MB) as a photosensitizer has emerged as an alternative treatment for skin cancers, such as squamous cell carcinoma (SCC).
Thayane Soares Lima   +4 more
doaj   +1 more source

Effect of an Oxygen-Based Mechanical Drug Delivery System on Percutaneous Permeation of Various Substances In Vitro

open access: yesPharmaceutics, 2022
Transdermal drug administration is an elegant method to overcome various side effects of oral or parenteral drug administration. Nevertheless, due to an effective skin barrier, which is provided by the stratum corneum, transdermal drug delivery is ...
Anna-Lena Elksnat   +4 more
doaj   +1 more source

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