Results 41 to 50 of about 1,233,961 (300)

Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation. [PDF]

open access: yes, 2016
Inadequate dietary Zn consumption increases susceptibility to esophageal and other cancers in humans and model organisms. Since Zn supplementation can prevent cancers in rodent squamous cell carcinoma (SCC) models, we were interested in determining if it
Druck, Teresa   +9 more
core   +2 more sources

Dermoscopy and Skin Cancer [PDF]

open access: yesDermatology Research and Practice, 2010
When I started my residency training about 11 years ago, I was immediately fascinated by the new morphologic dimension of skin lesions that is offered by dermoscopy, and accordingly, I focused my research on dermoscopy. At that time and as a young researcher, a recurrent statement was that “dermoscopy is not for future research as everything has ...
Zalaudek I   +4 more
openaire   +7 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Burden and Chemoprevention of Skin Cancer [PDF]

open access: yes, 2013
The incidence of skin cancer is increasing in the Netherlands since 1989, the first year of the Netherlands Cancer Registry (NCR). In 2010 more than 43,000 patients were newly diagnosed with skin cancer in the Netherlands. During a life time at least 1
Hollestein, L.M. (Loes)
core   +8 more sources

Male skin cancer incidence in Golestan province, Iran [PDF]

open access: yes, 2009
Objective: To evaluate province-specific estimates of incidence in males by age groups for skin cancer in the Golestan province, Iran. Methods: Data was collected from a cancer registry that was conducted by Health Deputy of Golestan province for a ...
Kabir, M.J., Marjani, A.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion

open access: yesCell Death and Disease
Melanoma is an aggressive skin cancer and highly lethal at advanced stages due to its high tumorigenicity and metastatic capacity. Changing the phenotype of cancer cells from one lineage to another, a process called transdifferentiation, leads to tumor ...
Yiman Wang   +15 more
doaj   +1 more source

CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES [PDF]

open access: yes, 2017
Cancer predisposition by the cooperation of genetic variants, such as single nucleotide polymorphisms (SNPs), may be of much greater significance to public health than previously appreciated.
Ortiz, Guadalupe J, IV
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

BAP1 tumor predisposition syndrome case report: pathological and clinical aspects of BAP1-inactivated melanocytic tumors (BIMTs), including dermoscopy and confocal microscopy

open access: yesBMC Cancer, 2019
Background BRCA1 associated-protein 1 (BAP1) tumor predisposition syndrome is associated with an increased risk for malignant mesotheliomas, uveal and cutaneous melanomas, renal cell carcinomas, and singular cutaneous lesions.
Bianca Costa Soares de Sá   +8 more
doaj   +1 more source

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