Results 31 to 40 of about 699,980 (314)

Paraneoplastic hyperleucocytosis in a melanoma patient after initiation of ipilimumab and nivolumab combination therapy

Journal for ImmunoTherapy of Cancer, 2018
Background Paraneoplastic hyperleucocytosis (PH) is sporadically seen in patients with advanced solid tumors. Case presentation We report a female patient with disseminated melanoma metastases.
Thilo Gambichler, E. Stockfleth, L. Susok   +2 more
doaj   +1 more source

Lasers for Skin Cancer

, 2013
The optimal laser treatment for skin cancer has not yet been developed. The first lasers that were used in an attempt to treat skin cancer emitted a continuous wave; however, significant nonspecific thermal heating occurred. In order to not extend beyond
Alqubaisy, Yasser A, Choudhary, Sonal, Sonal Choudhary, Katherine M. Ferris, McLeod, Michael P, Nouri, Keyvan, Michael P. McLeod, Ferris, Katherine M, Yasser A. Alqubaisy, Keyvan Nouri   +9 more
core   +1 more source

SunSmart? Skin cancer knowledge and preventive behaviour in a British population representative sample

, 2005
The incidence of skin cancer has risen rapidly in the UK over the last 20 years, prompting public health organizations to try and raise awareness of the dangers of sun exposure and the need to practice sun-safe behaviour.
Miles, Anne, Swanston, D., Miles, A, J. Waller, D. Swanston, Waller, J., Swanston, D, Hiom, S, Waller, J, S. Hiom, A. Miles, Hiom, S.   +11 more
core   +1 more source

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response

Stem Cell Reports, 2017
A point mutation in the BRAF gene, leading to a constitutively active form of the protein, is present in 45%–60% of patients and acts as a key driver in melanoma.
Mathias Bernhardt, Daniel Novak, Yassen Assenov, Elias Orouji, Nathalie Knappe, Kasia Weina, Maike Reith, Lionel Larribere, Christoffer Gebhardt, Christoph Plass, Viktor Umansky, Jochen Utikal   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Dermoscopy and Skin Cancer [PDF]

Dermatology Research and Practice, 2010
When I started my residency training about 11 years ago, I was immediately fascinated by the new morphologic dimension of skin lesions that is offered by dermoscopy, and accordingly, I focused my research on dermoscopy. At that time and as a young researcher, a recurrent statement was that “dermoscopy is not for future research as everything has ...
Zalaudek I, ARGENZIANO, Giuseppe, Marghoob AA, Pellacani G, Soyer HP   +4 more
openaire   +7 more sources

Machine Learning and Its Application in Skin Cancer

, 2021
Artificial intelligence (AI) has wide applications in healthcare, including dermatology. Machine learning (ML) is a subfield of AI involving statistical models and algorithms that can progressively learn from data to predict the characteristics of new ...
Clay J. Cockerell, Paweł Pietkiewicz, Anant Patil, Stephan Grabbe, Kinnor Das, Mario Giulini, Mohamad Goldust   +6 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer. [Elektronisk resurs]

, 2011
Ubiquitin and ubiquitin-related proteins posttranslationally modify substrates, and thereby alter the functions of their targets. The ubiquitination process is involved in various physiological responses, and dysregulation of components of the ubiquitin ...
Massoumi, Ramin,, Masoumi, Katarzyna,, Lund University., Hallgren, Gina,   +3 more
core   +1 more source

Impact of Social Media on Skin Cancer Prevention

, 2021
Despite the increasing prevalence of social media usage in health care contexts, its impact on skin cancer prevention and awareness has not been largely investigated. We conducted a review of literature on this topic with the objective of summarizing and
Neelam A. Vashi, Mayra B. C. Maymone, Henriette De La Garza   +2 more
core   +1 more source