Results 21 to 30 of about 4,372,786 (304)
Cells, 2023 Dermal stem cells (DSCs), which are progenitor cells of melanocytes, are isolated from human foreskin and cultivated as mixed cultures containing both DSCs and fibroblasts in varying proportions.
Christin Starzonek +8 more
doaj +1 more source
Clinical, dermoscopic and histopathologic findings of retiform hemangioendothelioma
Dermatology Practical & Conceptual, 2013 Retiform hemangioendothelioma (RH) is an uncommon vascular neoplasm of borderline malignancy that clinically develops as a solitary, gradually enlarging exophytic mass, nodule or plaque, most often on the lower limbs, upper limbs and trunk.
Amanda Mota +6 more
doaj +1 more source
Management of skin-sparing mastectomy: Results of a survey of German Hospitals [PDF]
, 2006 Background: The aim of this study was to evaluate the current management of skin-sparing mastectomy in German hospitals and to determine its oncologic safety.
Friese, K. +9 more
core +1 more source
Mitochondrial Sirtuins in Skin and Skin Cancers [PDF]
Photochemistry and Photobiology, 2020 AbstractMammalian sirtuins (SIRTs 1‐7) are a family of NAD+‐dependent deacetylases with distinct subcellular localization and biological functions that regulate various important cellular processes. Among these, SIRTs ‐3, ‐4 and ‐5 are located in the mitochondria and have been implicated in caloric restriction, oxidative stress, aging and various human
Shengqin Su +3 more
openaire +2 more sources
SOX2 and cancer: current research and its implications in the clinic
Clinical and Translational Medicine, 2014 SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and contains a high‐mobility group (HMG) domain, which permits highly specific DNA binding.
Kasia Weina, Jochen Utikal
doaj +1 more source
Sirtuins in Skin and Skin Cancers [PDF]
Skin Pharmacology and Physiology, 2017 The sirtuins are a family of proteins that comprise class III of the histone deacetylases. These NAD+-dependent proteins have been found to be intricately involved in a variety of important and skin-relevant cellular functions and processes, including aging, UV damage response, oxidative stress, and wound repair.
Liz Mariely, Garcia-Peterson +5 more
openaire +2 more sources
Journal for ImmunoTherapy of Cancer, 2018 Background Paraneoplastic hyperleucocytosis (PH) is sporadically seen in patients with advanced solid tumors. Case presentation We report a female patient with disseminated melanoma metastases.
Thilo Gambichler +2 more
doaj +1 more source
Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response
Stem Cell Reports, 2017 A point mutation in the BRAF gene, leading to a constitutively active form of the protein, is present in 45%–60% of patients and acts as a key driver in melanoma.
Mathias Bernhardt +11 more
doaj +1 more source
Dermoscopy and Skin Cancer [PDF]
Dermatology Research and Practice, 2010 When I started my residency training about 11 years ago, I was immediately fascinated by the new morphologic dimension of skin lesions that is offered by dermoscopy, and accordingly, I focused my research on dermoscopy. At that time and as a young researcher, a recurrent statement was that “dermoscopy is not for future research as everything has ...
Zalaudek I +4 more
openaire +7 more sources