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The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression
The immunosuppressive tumor microenvironment represents not only one of the key factors stimulating tumor progression but also a strong obstacle for efficient tumor immunotherapy.
Viktor Umansky +3 more
doaj +1 more source
Skin Lesion Analyser: An Efficient Seven-Way Multi-Class Skin Cancer Classification Using MobileNet
Skin cancer, a major form of cancer, is a critical public health problem with 123,000 newly diagnosed melanoma cases and between 2 and 3 million non-melanoma cases worldwide each year. The leading cause of skin cancer is high exposure of skin cells to UV
A Esteva +28 more
core +1 more source
BET inhibitors synergize with sunitinib in melanoma through GDF15 suppression
Cancer: a drug combination for combating melanoma Drugs that target proteins involved in issuing stop and start commands to cancer-related genes help to sensitize melanoma cells to a widely used anti-cancer therapy, leading to tumor shrinkage in mice ...
Furong Zeng +7 more
doaj +1 more source
Dermal stem cells (DSCs), which are progenitor cells of melanocytes, are isolated from human foreskin and cultivated as mixed cultures containing both DSCs and fibroblasts in varying proportions.
Christin Starzonek +8 more
doaj +1 more source
Histology of non-melanoma skin cancers. An Update [PDF]
Non-melanoma skin cancer (NMSC) is the most frequently diagnosed cancer in humans. Several different non-melanoma skin cancers have been reported in the literature, with several histologic variants that frequently cause important differential diagnoses ...
Cantisani, Carmen +4 more
core +2 more sources
Clinical, dermoscopic and histopathologic findings of retiform hemangioendothelioma
Retiform hemangioendothelioma (RH) is an uncommon vascular neoplasm of borderline malignancy that clinically develops as a solitary, gradually enlarging exophytic mass, nodule or plaque, most often on the lower limbs, upper limbs and trunk.
Amanda Mota +6 more
doaj +1 more source
Consumer preferences for teledermoscopy screening to detect melanoma early [PDF]
Introduction: ‘Store and forward’ teledermoscopy is a technology with potential advantages for melanoma screening. Any large-scale implementation of this technology is dependent on consumer acceptance.
Janda, Monika +3 more
core +2 more sources
Personalised electronic messages to improve sun protection in young adults [PDF]
The incidence of all skin cancers, including melanoma, continues to rise. It is well known that ultraviolet (UV) radiation is the main environmental risk factor for skin cancer, and excessive exposure at a young age increases the risk of developing skin ...
Alison Marshall +9 more
core +2 more sources
Mitochondrial Sirtuins in Skin and Skin Cancers [PDF]
AbstractMammalian sirtuins (SIRTs 1‐7) are a family of NAD+‐dependent deacetylases with distinct subcellular localization and biological functions that regulate various important cellular processes. Among these, SIRTs ‐3, ‐4 and ‐5 are located in the mitochondria and have been implicated in caloric restriction, oxidative stress, aging and various human
Shengqin Su +3 more
openaire +2 more sources
Lifetime prevalence of non-melanoma and melanoma skin cancer in Australian recreational and competitive surfers [PDF]
Background/Purpose Surfing is one of the most popular outdoor aquatic activities in Australia with an estimated 2.7 million recreational surfers; however, Australia has long been recognized as having the highest incidence of melanoma in the world, and it ...
Climstein, Mike +3 more
core +1 more source

