Results 61 to 70 of about 1,239,936 (299)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Multidisciplinary Management of Palpebral Melanoma

Plastic and Reconstructive Surgery, Global Open
Summary:. Ocular melanoma encompasses the uveal tract, conjunctiva, eyelid, and orbit. Palpebral localization is extremely infrequent, constituting less than 1% of skin melanomas, the main treatment of which is surgical.
Marcelo Chávez Díaz, MD, Otto Ziegler Rodríguez, MD, FACS, Gonzalo Ziegler Rodríguez, MD, Jaime Montes Gil, MD, Gabriel De la Cruz Ku, MD, Carla Carina Cedrón Lenci, MD, Otto Ziegler-Gutierrez, MD   +6 more
doaj   +1 more source

Occupational skin cancers [PDF]

Occupational Medicine, 2004
Skin cancer due to occupation is more common than is generally recognized, although it is difficult to obtain an accurate estimate of its prevalence. Over the past two centuries, occupational skin cancers have particularly been due to industrial exposure of men (it seems more so than women) to chemical carcinogens such as polycyclic hydrocarbons (e.g ...
openaire   +2 more sources

Dermoscopy and Skin Cancer [PDF]

Dermatology Research and Practice, 2010
When I started my residency training about 11 years ago, I was immediately fascinated by the new morphologic dimension of skin lesions that is offered by dermoscopy, and accordingly, I focused my research on dermoscopy. At that time and as a young researcher, a recurrent statement was that “dermoscopy is not for future research as everything has ...
Zalaudek I, ARGENZIANO, Giuseppe, Marghoob AA, Pellacani G, Soyer HP   +4 more
openaire   +6 more sources

Promotion of Skin Protection in Children in Waterbury, VT [PDF]

, 2017
Background: Vermont has among the highest rates of skin cancer in the nation. Between 2001 and 2005, Vermont had the highest incidence of melanoma of any state, 63% higher than the national average.
Sullivan, Kelsey M
core   +1 more source

Meta‐analysis of the association between sodium‐glucose co‐transporter‐2 inhibitors and risk of skin cancer among patients with type 2 diabetes [PDF]

, 2018
A slight increase in melanoma risk was observed among sodium‐glucose co‐transporter‐2 (SGLT‐2) inhibitor users in the regular reports. However, the association remains uncertain.
Bailey, Barnett, Bode, Brockhaus, Cefalu, Chen, Deeks, DeFronzo, Ferrannini, Fralick, Grunberger, Haring, Higgins, Higgins, Häring, Jabbour, Kashiwagi, Kohler, Kovacs, Leiter, Lewin, Li, Nauck, Neal, Ridderstrale, Roden, Søfteland, Wanner, Yang, Zaccardi, Zinman   +30 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Efficacy assessment of oxygen flow assisted administration of topical methotrexate (OFA‐MTX5%) for superficial basal cell carcinoma assessed by optical coherence tomography

JEADV Clinical Practice, 2023
Background Oxygen‐flow‐assisted topical administration of 5% methotrexate (OFAMTX5%) was recently described as a painless therapeutic option with good cosmetic results for superficial basal cell carcinoma (sBCC).
Gilles Absil, Eve Lebas, Arjen F. Nikkels   +2 more
doaj   +1 more source

Vitiligo and autoimmune thyroid disorders [PDF]

, 2017
Vitiligo represents the most common cause of acquired skin, hair and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte ...
Baldini, Enke, Carbotta, Giovanni, Catania, Antonio, D'Armiento, Eleonora, Odorisio, Teresa, Persechino, Severino, Pironi, Daniele, Rendina, Roberta, Sorrenti, Salvatore, Tartaglia, Francesco, Ulisse, Salvatore   +10 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source