Results 71 to 80 of about 699,980 (314)

Multidisciplinary Management of Palpebral Melanoma

Plastic and Reconstructive Surgery, Global Open
Summary:. Ocular melanoma encompasses the uveal tract, conjunctiva, eyelid, and orbit. Palpebral localization is extremely infrequent, constituting less than 1% of skin melanomas, the main treatment of which is surgical.
Marcelo Chávez Díaz, MD, Otto Ziegler Rodríguez, MD, FACS, Gonzalo Ziegler Rodríguez, MD, Jaime Montes Gil, MD, Gabriel De la Cruz Ku, MD, Carla Carina Cedrón Lenci, MD, Otto Ziegler-Gutierrez, MD   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Modified UQ Flap: An Alternative for Other Flaps

Plastic and Reconstructive Surgery, Global Open, 2023
Mohammadreza Hassani, MD, MMed (Skin Cancer), Cliff Rosendahl, MBBS, PhD   +1 more
doaj   +1 more source

Automatic segmentation of skin cancer images using adaptive color clustering [PDF]

, 2006
This paper presents the development of an adaptive image segmentation algorithm designed for the identification of the skin cancer and pigmented lesions in dermoscopy images. The key component of the developed algorithm is the Adaptive Spatial K-Means (A-
Ilea, Dana E., Whelan, Paul F.
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Neural crest-associated gene FOXD1 induces an immunosuppressive microenvironment by regulating myeloid-derived suppressor cells in melanoma

Journal for ImmunoTherapy of Cancer
Background Neural crest-associated genes play pivotal roles in tumor initiation, progression, and the intricate dynamics of the tumor microenvironment (TME).
Jochen Sven Utikal, Viktor Umansky, Kilian Wistuba-Hamprecht, Qian Sun, Rebekka Bitsch, Feyza Gül Özbay Kurt, Daniel Novak, Yuxin Zhang, Shibo Liu, Rui Han, Nina Wang, Juliane Poelchen, Mareike Peter, Huizi Wu, Yiman Wang, Sandra Pardo, Lidong Gong   +16 more
doaj   +1 more source

Enhanced chlorhexidine skin penetration with eucalyptus oil [PDF]

, 2010
Background Chlorhexidine digluconate (CHG) is a widely used skin antiseptic, however it poorly penetrates the skin, limiting its efficacy against microorganisms residing beneath the surface layers of skin. The aim of the current study was to improve the
Conway, Barbara R, Anthony C Hilton, Elliott Tom SJ, Lambert Peter A, Hilton, Anthony C, Karpanen Tarja J, Peter A Lambert, Tarja J Karpanen, Hilton Anthony C, Tony Worthington, Worthington, Tony, Karpanen, Tarja J., Elliott, T.S.J., Lambert, P.A., Karpanen, Tarja J, Worthington, T., Tom SJ Elliott, Hilton, A.C., Elliott, Tom S J, Conway Barbara R, Hilton, Anthony C., Worthington Tony, Conway, Barbara R., Karpanen, T.J., Lambert, Peter A, Lambert, Peter A., Barbara R Conway   +26 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source