Results 81 to 90 of about 7,017,143 (393)

Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism [PDF]

, 2009
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantable tumours in testing the efficacy of vaccines.
Germain J. Fernando, Jie Zhong, Marion E. G. Brunck, Xiao Song Liu   +3 more
core   +2 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Primary Cutaneous CD30+ Anaplastic Large T Cell Lymphoma in a Patient Treated with Cyclosporine for Actinic Reticuloid

Case Reports in Dermatological Medicine, 2020
Actinic reticuloid (AR)—a subtype of chronic actinic dermatitis—clinically and histopathologically shows lymphoma-like features. We report a male patient initially diagnosed with erythrodermic cutaneous T cell lymphoma (CTCL) who developed severe ...
T. Gambichler, N. Patsinakidis, L. Susok, M. H. Segert, M. Doerler   +4 more
doaj   +1 more source

A Clinicopathological Analysis of Melanocytic Nevi: A Retrospective Series

Frontiers in Medicine, 2021
Purpose: Melanocytic nevi are common cutaneous lesions. This study aimed to demonstrate the concordance and discordance between clinical and histopathological diagnoses of melanocytic nevi and the importance of histological evaluation in differentiating ...
Panpan Liu, Panpan Liu, Panpan Liu, Juan Su, Juan Su, Juan Su, Xuanwei Zheng, Xuanwei Zheng, Xuanwei Zheng, Mingliang Chen, Mingliang Chen, Mingliang Chen, Xiang Chen, Xiang Chen, Xiang Chen, Jie Li, Jie Li, Jie Li, Cong Peng, Cong Peng, Cong Peng, Yehong Kuang, Yehong Kuang, Yehong Kuang, Wu Zhu, Wu Zhu, Wu Zhu   +26 more
doaj   +1 more source

Computer-aided diagnosis of skin cancer based on soft computing techniques

Open Medicine, 2020
Skin cancer is a type of disease in which malignant cells are formed in skin tissues. However, skin cancer is a dangerous disease, and an early detection of this disease helps the therapists to cure this disease.
Zhiying Xu, Fatima Rashid Sheykhahmad, N. Ghadimi, Navid Razmjooy   +3 more
semanticscholar   +1 more source

Classification of Several Skin Cancer Types Based on Autofluorescence Intensity of Visible Light to Near Infrared Ratio [PDF]

, 2009
Skin cancer is a Malignant growth on the skin caused by many factors. The most common skin cancers are Basal Cell Cancer (BCC) and Squamous Cell Cancer (SCC).
Dwira, S. (Surya), Ibrahim, A. S. (Anwar), Kusmardi, K. (Kusmardi), Patiatta, R. (Rino), Tedjo, A. (Aryo)   +4 more
core  

Incidence and public health burden of sunburn among beachgoers in the United States. [PDF]

, 2020
The beach environment creates many barriers to effective sun protection, putting beachgoers at risk for sunburn, a well-established risk factor for skin cancer.
Arnold, Benjamin F, Colford, John M, DeFlorio-Barker, Stephanie, Holman, Dawn, Landolfi, Robert, Sams, Elizabeth A, Schiff, Kenneth C, Wade, Timothy J, Weisberg, Stephen B   +8 more
core   +2 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Skin cancer and immunosuppression [PDF]

Critical Reviews in Oncology/Hematology, 2005
All immunosuppressive treatments, either pharmacological or physical, have the potential to impair the skin immune system network of cells and cytokines, thus leading to an increased incidence of skin cancer. Since skin cancer in transplant recipients may show uncommon clinical features and have an unusually aggressive course, transplant patients ...
G. GERLINI, ROMAGNOLI, PAOLO, PIMPINELLI, NICOLA   +2 more
openaire   +3 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source