Results 81 to 90 of about 6,271,834 (365)

Association of Psoriasis With Anxiety and Depression: A Case–Control Study in Chinese Patients

Frontiers in Medicine, 2021
Background: Patients with psoriasis are prone to suffer from anxiety and depression during their lifetime. This study aimed to investigate the association of psoriasis with anxiety and depression in Chinese patients.Methods: A case-control study in ...
Danrong Jing, Danrong Jing, Danrong Jing, Hui Xiao, Hui Xiao, Hui Xiao, Minxue Shen, Minxue Shen, Minxue Shen, Minxue Shen, Xiang Chen, Xiang Chen, Xiang Chen, Xi Han, Yehong Kuang, Yehong Kuang, Yehong Kuang, Wu Zhu, Wu Zhu, Wu Zhu, Yi Xiao, Yi Xiao, Yi Xiao   +22 more
doaj   +1 more source

Skin cancer and immunosuppression [PDF]

Critical Reviews in Oncology/Hematology, 2005
All immunosuppressive treatments, either pharmacological or physical, have the potential to impair the skin immune system network of cells and cytokines, thus leading to an increased incidence of skin cancer. Since skin cancer in transplant recipients may show uncommon clinical features and have an unusually aggressive course, transplant patients ...
G. GERLINI, ROMAGNOLI, PAOLO, PIMPINELLI, NICOLA   +2 more
openaire   +3 more sources

The efficacy and safety of sunscreen use for the prevention of skin cancer

Canadian Medical Association Journal, 2020
KEY POINTS In Canada, more than 80 000 cases of skin cancer are diagnosed every year.[1][1] Because exposure to ultraviolet radiation is estimated to be associated with 80%–90% of skin cancers, the use of sunscreen — which blocks ultraviolet radiation ...
Megan Sander, M. Sander, T. Burbidge, J. Beecker   +3 more
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Mechanisms of UV-induced mutations and skin cancer

Genome Instability & Disease, 2020
Ultraviolet (UV) irradiation causes various types of DNA damage, which leads to specific mutations and the emergence of skin cancer in humans, often decades after initial exposure.
G. Pfeifer
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Multidisciplinary Management of Palpebral Melanoma

Plastic and Reconstructive Surgery, Global Open
Summary:. Ocular melanoma encompasses the uveal tract, conjunctiva, eyelid, and orbit. Palpebral localization is extremely infrequent, constituting less than 1% of skin melanomas, the main treatment of which is surgical.
Marcelo Chávez Díaz, MD, Otto Ziegler Rodríguez, MD, FACS, Gonzalo Ziegler Rodríguez, MD, Jaime Montes Gil, MD, Gabriel De la Cruz Ku, MD, Carla Carina Cedrón Lenci, MD, Otto Ziegler-Gutierrez, MD   +6 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Distribution of sentinel nodes from parotid tumors–A feasibility study

Cancer Medicine, 2023
Background Optimum management of the N0 neck is unresolved in parotid salivary gland cancer. Sentinel node biopsy (SNB) can reliably detect microscopic lymph node metastasis and its´ clinical use is increasing for head and neck tumors. The object of this
Lalle Hammarstedt‐Nordenvall, Rusana Bark, Alexandra Elliot, Mathias Von Beckerath, Caroline Gahm   +4 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source