Results 91 to 100 of about 12,125,335 (363)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Experience of Use General Air Cryotherapy for Correction of Psoriasis

Медицинский вестник Юга России, 2012
Purpose: We investigated the efficacy and safety of general air cryotherapy with addition of the moisturizing agent Xemose cream (Uriage cosmetic line) for correction of psoriasis.
Ya. Yu. Solonchenko, B. Ye. Yevtushenko, S. V. Grebennikova   +2 more
doaj  

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

Skin diseases are more common than we think: screening results of an unreferred population at the Munich Oktoberfest

Journal of the European Academy of Dermatology and Venereology, 2019
Skin diseases are ranked as the fourth most common cause of human illness, resulting in an enormous non‐fatal burden. Despite this, many affected people do not consult a physician.
L. Tizek, L. Tizek, M. Schielein, M. Schielein, Florian Seifert, Tilo Biedermann, A. Böhner, Alexander Zink   +7 more
semanticscholar   +1 more source

Psychosocial impact of skin diseases: A population-based study

PLoS ONE, 2020
Background While it is well established that skin disease places significant psychosocial burden on a patient’s wellbeing, its effects have rarely been examined in Asian populations.
Y. Yew, A. Kuan, Lixia Ge, C. Yap, B. Heng   +4 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

High Glucosinolate Mustard and Potato Trial [PDF]

, 2013
High glucosinolate mustard (HGM) can be planted as a cover crop to suppress weeds and disease. Studies have shown a reduction in soil-borne diseases, as well as advantages in mitigating weed pressure, after planting HGM cover crops.
Cummings, Erica, Darby, Heather, Harwood, Hannah, Monahan, Susan   +3 more
core   +1 more source

Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

Frontiers in Immunology, 2019
Tyrosine kinases relay signals from diverse leukocyte antigen receptors, innate immune receptors, and cytokine receptors, and therefore mediate the recruitment and activation of various leukocyte populations. Non-receptor tyrosine kinases of the Jak, Src,
K. Szilveszter, T. Németh, A. Mócsai
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Somatic Variants of KRT1/KRT10 Identified by Next-generation Sequencing in Patients with Epidermal Nevi

Acta Dermato-Venereologica
is missing (Short communication)
Shuya Sun, Ran Mo, Zhiming Chen, Yong Yang, Ruiyu Xiang   +4 more
doaj   +1 more source