Results 191 to 200 of about 22,408 (233)
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RETINOID STIMULATES EPIDERMAL OUTGROWTH OF PIG SKIN EXPLANTS
The Journal of Dermatology, 1981ABSTRACTUsing a pig explant culture system, the effects of retinoids on pig epidermal cells were studied. Ro 10‐9359 slightly stimulated epidermal outgrowth, but this effect was not significant. Ro 10‐1670 (a metabolite of Ro 10‐9359) significantly stimulated epidermal outgrowth.
T, Aoyagi +5 more
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A latent collagenase from embryonic human skin explants.
Journal of biochemistry, 1977Collagenase released from embryonic and adult human skin explants has been studied with special reference to the latency of the enzyme. 1) Embryonic human skin explants showed a much higher capacity for collagenase production than did adult skin, on the basis of unit weight of tissue.
H, Shinkai, Y, Nagai
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Phenotype of Cells Migrated from Human Skin Explants
1995Dendritic cells (DC) are very efficient antigen presenting cells, distributed in many tissues and organs (1). In the skin, they are characterized by CDla expression and the most extensively studied cell among them is the epidermal Langerhans cell. However, the dermis contains also a population of CDla+ cells with potent antigen presenting capacities (2,
C D, Richters +3 more
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Proteoglycan synthesis in human skin and burn scar explant cultures
Burns, 1991The synthesis of proteoglycans (PG) by normal human skin, and normal and hypertrophic scars were compared using tissue explants in culture. Newly synthesized PG were labelled with [35S]Na2SO4. Significant differences were found in the proportion of [35S]-radio-labelled incorporation of PG in the tissue and accumulation of [35S]PG in culture medium in ...
H G, Garg +4 more
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Skin explant cultures as a source of keratinocytes for cultivation
Cell and Tissue Banking, 2012Cultivated human keratinocytes can be used successfully in the treatment of burn patients, but efforts to heal burns and other wounds can be hampered by the very small skin biopsies available for cultivation of transplantable keratinocyte sheets.
J, Dragúňová, P, Kabát, J, Koller
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International Journal of Cosmetic Science, 2011
SynopsisGlycation is an ageing reaction of naturally occurring sugars with dermal proteins, whose clinical signs may appear in vivo around age 30, and increases steadily/regularly with age. The suppleness of the dermis is affected by the formation of bridges between proteins and sugars (Maillard’s reaction).
P, Gasser +6 more
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SynopsisGlycation is an ageing reaction of naturally occurring sugars with dermal proteins, whose clinical signs may appear in vivo around age 30, and increases steadily/regularly with age. The suppleness of the dermis is affected by the formation of bridges between proteins and sugars (Maillard’s reaction).
P, Gasser +6 more
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Effects of gemfibrozil on in vitro cultured normal human skin explants
International Journal of Dermatology, 1999Abstract Background Several lipid‐lowering agents, when given topically, show a profound effect on skin morphology. Because of low bioavailability of these drugs for keratinocytes, the incidence is extremely low clinically. The most appropriate way to study the effect of hypolipidemic drugs on keratinocytes is by artificial exposure of the skin to high
WOLF R +4 more
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An innovative bioreactor for skin explants model
2019Skin explants have been maintained in an innovative ...
Enrica Cappellozza +2 more
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Visible effects of rapamycin (sirolimus) on human skin explants in vitro
Archives of Dermatological Research, 2012In this manuscript, we report observations of the effects of rapamycin in an organotypic culture of human skin explants. The tissues were cultured for 5 days at the air-liquid interface or in submersed conditions with media with and without rapamycin at 2 nM concentration.
Antonio, Peramo, Cynthia L, Marcelo
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Fluorescence imaging of reepithelialization from skin explant cultures on acellular dermis
Wound Repair and Regeneration, 2004Reconstituted skin models are valuable tools in studies of cutaneous biology although they are not generally devised to visualize and quantify the time course of reepithelialization. We describe a skin explant culture technique coupled with vital microscopy allowing sequential imaging of epithelial outgrowth while maintaining the tissue in culture ...
Hongguang, Lu, Ola, Rollman
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