Results 211 to 220 of about 12,047 (235)
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Visible effects of rapamycin (sirolimus) on human skin explants in vitro

Archives of Dermatological Research, 2012
In this manuscript, we report observations of the effects of rapamycin in an organotypic culture of human skin explants. The tissues were cultured for 5 days at the air-liquid interface or in submersed conditions with media with and without rapamycin at 2 nM concentration.
Antonio, Peramo, Cynthia L, Marcelo
openaire   +2 more sources

Proteoglycan synthesis in human skin and burn scar explant cultures

Burns, 1991
The synthesis of proteoglycans (PG) by normal human skin, and normal and hypertrophic scars were compared using tissue explants in culture. Newly synthesized PG were labelled with [35S]Na2SO4. Significant differences were found in the proportion of [35S]-radio-labelled incorporation of PG in the tissue and accumulation of [35S]PG in culture medium in ...
H G, Garg   +4 more
openaire   +2 more sources

Effects of gemfibrozil on in vitro cultured normal human skin explants

International Journal of Dermatology, 1999
Abstract Background Several lipid‐lowering agents, when given topically, show a profound effect on skin morphology. Because of low bioavailability of these drugs for keratinocytes, the incidence is extremely low clinically. The most appropriate way to study the effect of hypolipidemic drugs on keratinocytes is by artificial exposure of the skin to high
WOLF R   +4 more
openaire   +3 more sources

A latent collagenase from embryonic human skin explants.

Journal of biochemistry, 1977
Collagenase released from embryonic and adult human skin explants has been studied with special reference to the latency of the enzyme. 1) Embryonic human skin explants showed a much higher capacity for collagenase production than did adult skin, on the basis of unit weight of tissue.
H, Shinkai, Y, Nagai
openaire   +3 more sources

Pemphigus antibody action on skin explants: kinetics of acantholytic changes and stability of antigens in tissue cultures of normal monkey skin explants.

Archives of dermatology, 1977
The pathogenic effect of the intercellular antibodies of pemphigus was studied by using organ culture of monkey skin. Skin explants that were grown on sera with intercellular antibody titers of 320 or greater fixed these antibodies within one day as demonstrated by direct immunofluorescence for IgG. None of the control sera gave such staining patterns.
J S, Deng   +3 more
openaire   +1 more source

An improved human skin explant culture method for testing and assessing personal care products

Journal of Cosmetic Dermatology, 2023
Linli Zhou   +2 more
exaly  

Pemphigus Antibody Action on Skin Explants

Archives of Dermatology, 1977
openaire   +1 more source

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