Results 191 to 200 of about 12,047 (235)

Skin explant cultures as a source of keratinocytes for cultivation

Cell and Tissue Banking, 2012
Cultivated human keratinocytes can be used successfully in the treatment of burn patients, but efforts to heal burns and other wounds can be hampered by the very small skin biopsies available for cultivation of transplantable keratinocyte sheets.
Peter Kabat
exaly   +3 more sources

Effects of the re‐innervation of organotypic skin explants on the epidermis

open access: yesExperimental Dermatology, 2012
Abstract:  The nervous system takes part in skin homeostasis and interacts with skin cells. In in vitro organotypic skin models, these interactions are lost owing to the absence of nerve endings. We have developed an in vitro organotypic skin model based on a re‐innervated human skin explant using primary sensory neurons from the dorsal root ganglia of
Nicolas, Lebonvallet   +10 more
openaire   +4 more sources

Skin Explant Model of Human Graft-versus-Host Disease: Prediction of Clinical Outcome and Correlation with Biological Risk Factors

open access: yesBiology of Blood and Marrow Transplantation, 2006
A human skin explant model has been used to predict the clinical outcome and to study the immunopathology of human graft-versus-host disease (GVHD).
Matthew Collin   +2 more
exaly   +2 more sources

Re‐evaluation of skin‐explant model in graft‐versus‐host disease prediction

open access: yesClinical Transplantation, 1995
An in vitro skin explant model has been proposed for prediction of graft versus host disease and reported to be highly sensitive and specific for this purpose.
Oya Gurbuz, S Küllü, Aydin Sav
exaly   +2 more sources

Histological correlation between different centers using the skin explant model to predict graft-versus-host disease following bone marrow transplantation

open access: yesHuman Immunology, 2001
Acute graft-versus-host disease (GVHD) remains the major complication of allogeneic stem cell transplantation (SCT) with an incidence of 40-60% and a mortality of up to 50%.
L Sviland   +2 more
exaly   +3 more sources

An explant model for the investigation of skin adaptation to mechanical stress

IEEE Transactions on Biomedical Engineering, 2002
A test apparatus was developed to investigate the effects of mechanical stress application on collagen remodeling in skin. The system maintained a 4.5-cm x 5.5-cm skin explant at an air interface with controlled temperature, relative humidity (RH), and carbon dioxide concentration [CO2] while allowing controlled compressive and shear forces to be ...
Joan E. Sanders   +3 more
openaire   +2 more sources

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