Results 81 to 90 of about 2,027,719 (303)

Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an alpha-1 adrenoceptor agonist [PDF]

, 2011
Iontophoresis of aradrenoceptor agonists in the human forearm evoke axon reflex vasodilatation, possibly due to an accumulation of inflammatory agents at the site of iontophoresis.
Drummond, P.D.
core  

Brain-Skin Connection: Stress, Inflammation and Skin Aging [PDF]

Inflammation & Allergy-Drug Targets, 2014
The intricate relationship between stress and skin conditions has been documented since ancient times. Recent clinical observations also link psychological stress to the onset or aggravation of multiple skin diseases. However, the exact underlying mechanisms have only been studied and partially revealed in the past 20 years or so.
Chen, Ying, Lyga, John
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation [PDF]

, 2018
Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear granulocytes. Although preclinical studies have provided insights into the mechanisms of disease
Tom Hartwig, Lukas Flatz, Burkhard Becher, Hartwig, Tom, Curdin Conrad, Yawalkar, Nikhil, Schlapbach, Christoph, Schreiner, B., Alexander Navarini, Pascale Zwicky, Christoph Schlapbach, Conrad, Curdin, Reinhard Dummer, Cheng, Phil; https://orcid.org/, Yawalkar, N., Navarini, A., Schreiner, Bettina, Cheng, P., Becher, Burkhard, Dummer, R., Schlapbach, C., Becher, B., Phil Cheng, Dummer, Reinhard, Zwicky, P., Nikhil Yawalkar, Hartwig, T., Bettina Schreiner, Flatz, Lukas, Flatz, L., Cheng, Phil, Becher, Burkhard; https://orcid.org/, Conrad, C., Navarini, Alexander, Zwicky, Pascale   +34 more
core   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effects of resveratrol in ınflammatory arthritis

, 2007
Inflammation, Vol. 30, Nos. 1Y2, April 2007 ( 2006)Summary: Nuclear factor kappa B (NF-kB), is a pivotal transcription factor involved in the activation of the TNF-a and IL-1b genes.
Baysal, Özlem, Esenkaya, İrfan, Mızrak, Bülent, Elmalı, Nurzat, Harma, Ahmet   +4 more
core   +1 more source

Skin ageing [PDF]

, 2007
Cutaneous ageing manifests itself as a progressive reduction in maximum function and reserve capacity of skin tissue. It is not a unique and uniform biological event. Skin comprises three layers: epidermis, dermis and subcutaneous tissue.
Brincat, Mark P., Calleja-Agius, Jean, Muscat Baron, Yves   +2 more
core   +1 more source

Effects of VitabridC¹²on Skin Inflammation [PDF]

Annals of Dermatology, 2017
VitabridC12 is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide).In this study, we aimed to investigate the effects of VitabridC12 on psoriasis and atopic dermatitis.Mice with imiquimod-induced psoriasis or Dermatophagoides farinae-induced atopic dermatitis were applied with VitabridC12.
Lee, Ji Hyun, Jeon, Yoon-Jae, Choi, Jung Hye, Kim, Hae Young, Kim, Tae-Yoon   +4 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Corrigendum: Cutaneous kinase activity correlates with treatment outcomes following PI3K delta inhibition in mice with experimental pemphigoid diseases

Frontiers in Immunology, 2022
Saeedeh Ghorbanalipoor, Shirin Emtenani, Melissa Parker, Mayumi Kamaguchi, Colin Osterloh, Manuela Pigors, Natalie Gross, Stanislav Khil’chenko, Anika Kasprick, Sabrina Patzelt, Diana Wortmann, Ibrahim O. Ibrahim, Kentaro Izumi, Stephanie Goletz, Katharina Boch, Kathrin Kalies, Katja Bieber, Paul Smith, Enno Schmidt, Ralf J. Ludwig   +19 more
doaj   +1 more source