Results 171 to 180 of about 1,246,297 (290)

AKT and PERP Show Higher Expression in Precancerous than in Malignant Skin Neoplasms: Profiling in an Animal Model of Sequential Skin Carcinogenesis. [PDF]

J Pers Med
Vairaktari E, Schramm A, Vairaktari G, Derka S, Wilde F, Sakkas A, Yapijakis C, Kouri M, Balakas A, Lazaris A, Ebeling M, Vassiliou S.   +11 more
europepmc   +1 more source

Study of skin neoplasms in a university hospital: integration of anatomopathological records and its interface with the literature. [PDF]

An Bras Dermatol, 2019
Rezende HD, Almeida APM, Shimoda E, Milagre ACX, Almeida LM.   +4 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

The role of immunohistochemistry expression of COX-2 in differentiating pigmented benign and malignant skin neoplasms. [PDF]

Med J Islam Repub Iran, 2019
Ghasemi M, Afshar P, Sheidaei S, Moeini Y, Vahedi Larijani L.   +4 more
europepmc   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Immunohistochemical Investigation of Mutant BRAF V600E in Common Pigmented Skin Neoplasms, Study on a Sample of Iranian Patients. [PDF]

Iran J Pathol, 2019
Ghasemi M, Vahedi Larijani L, Emadian O, Yazdani J, Sajadianfar A, Abediankenari S.   +5 more
europepmc   +1 more source

Skin cancer prevention progress report 2019

In July 2014, the Office of the Surgeon General released The Surgeon General\u2019s Call to Action to Prevent Skin Cancer, establishing skin cancer prevention as a high priority for ou r nation.

core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Pigmentation phenotype, photosensitivity and skin neoplasms in patients with myotonic dystrophy. [PDF]

Eur J Neurol, 2017
Gadalla SM, Hilbert JE, Martens WB, Givens S, Moxley RT, Greene MH.   +5 more
europepmc   +1 more source