Results 101 to 110 of about 62,571 (334)

Effects of Solvents on Skin Permeation of Formoterol Fumarate

open access: yesBiological and Pharmaceutical Bulletin, 2006
Effects of various chemicals applied as penetration enhancers on the permeation of formoterol fumarate (FF) across excised rat skin were investigated. Remarkable enhancement was noted with terpenes, fatty acid esters, and higher alcohols, whereas no significant influence was observed in the case of lower alcohols, pyrrolidones, and amines.
Hitoshi Yamauchi   +5 more
openaire   +4 more sources

High performance blended membranes using a novel preparation technique [PDF]

open access: yes, 2008
The possibility of applying novel microwave (MW) technique in the dissolution of polyethersulfone (PES) and lithium halides in aprotic solvent is studied.
Ahmed, Iqbal   +3 more
core  

A comparative study of the in vitro permeation of ibuprofen in mammalian skin, the PAMPA model and silicone membrane [PDF]

open access: yes, 2016
Human skin remains the membrane of choice when conducting in vitro studies to determine dermal penetration of active pharmaceutical ingredients or xenobiotics. However there are ethical and safety issues associated with obtaining human tissue.
Avnish Patel   +6 more
core   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Influence of pH on Skin Permeation of Amino Acids

open access: yesJournal of Pharmacy and Pharmacology, 1996
Abstract Skin permeation of amino acids through excised rat skin was measured at various pH values. The permeabilities varied with the donor pH and amino acid, indicating that each ionic species of amino acid may have a different permeability.
Chisato Uozumi   +6 more
openaire   +3 more sources

Sodium lauryl sulphate/ultrasound combination for transcutaneous vaccine delivery: effect of changing sodium lauryl sulphate concentration on antigen permeation, cavitation and skin damage [PDF]

open access: yes, 2006
Low frequency ultrasound in combination with Sodium Lauryl Sulphate (SLS), a known transdermal chemical enhancer has been found to enhance delivery of molecules through the skin.
Dahlan, A, Murdan, S
core  

Morphological characterization of a polymeric microfiltration membrane by synchrotron radiation computed microtomography [PDF]

open access: yes, 2007
Most commercial polymeric membranes are prepared by phase inversion. The performance of the membranes depends greatly on the morphology of the porous structure formed during the different steps of this process.
Meireles, Martine   +2 more
core   +2 more sources

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

open access: yesAdvanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte   +6 more
wiley   +1 more source

Combined approach of nanoemulgel and microneedle pre-treatment as a topical anticellulite therapy

open access: yesADMET and DMPK
Background and purpose: Cellulite is caused by changes in the metabolism of the fatty tissue beneath the skin. Methylxanthines and retinoids are commonly added to the different anticellulite products. However, their topical permeation into the dermis is
Hiba Imad Hameed   +1 more
doaj   +1 more source

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