Results 31 to 40 of about 62,571 (334)
Pharmaceutics, 2020 Polymer-based solid microstructures (MSts) have the potential to significantly increase the quantity and range of drugs that can be administered across the skin.
Raha Rahbari +6 more
doaj +1 more source
Permeation of skin with (C60) fullerene dispersions [PDF]
Engineering in Life Sciences, 2017 Dispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations.
Sá, M. +4 more
openaire +4 more sources
Using pH abnormalities in diseased skin to trigger and target topical therapy [PDF]
, 2011 Purpose: The pH discrepancy between healthy and atopic dermatitis skin was identified as a site specific trigger for delivering hydrocortisone from microcapsules.
Donaldson, M. X. +3 more
core +1 more source
In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations
The Scientific World Journal, 2013 This study is focused on in vitro permeation of the original Czech compound, a skin/mucosa tissue regeneration promoter, known under the international nonproprietary name “alaptide,” in micronized and nanonized forms.
Radka Opatrilova +4 more
doaj +1 more source
Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion
Molecules, 2017 This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN).
Qiang Zu +4 more
doaj +1 more source
Enhancement of Skin Delivery of Drugs Using Proposome Depends on Drug Lipophilicity
Pharmaceutics, 2021 The study aims to investigate the propylene glycol-based liposomes named ‘proposomes’ in enhancing skin permeation of drugs with different physicochemical properties. Ibuprofen, tofacitinib citrate, rhodamine B, and lidocaine were loaded into proposomes.
Himanshu Kathuria +7 more
doaj +1 more source
Accelerating topical anaesthesia using microneedles [PDF]
, 2017 Background/Aims: Topical anaesthetics reduce pain during venous access procedures in children. However, clinical use is hindered by a significant anaesthetic onset time.
Birchall, James +4 more
core +2 more sources
Pharmaceutics, 2016 Generally, the blood and skin concentration profiles and steady-state skin concentration of topically applied or exposed chemicals can be calculated from the in vitro skin permeation profile. However, these calculation methods are particularly applicable
Fadli Mohd +4 more
doaj +1 more source
Frontiers in Materials, 2022 Among different topical drug delivery systems, nanoemulsions (NEs) are attractive due to enhanced skin permeation potential and minimum toxicity. Topical nanoemulgels (NEMGELs) contain both gelling agents and NEs and thus can enhance skin permeation with
Soliman Mohammadi-Samani +6 more
doaj +1 more source
Recent developments in skin mimic systems to predict transdermal permeation [PDF]
, 2015 In recent years there has been a drive to create experimental techniques that can facilitate the accurate and precise prediction of transdermal permeation without the use of in vivo studies.
Waters, Laura J.
core +1 more source