Results 81 to 90 of about 72,676 (214)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Deciphering Nazi Racial Sorting: The Challenges of Attempting a Big Data Approach

Berichte zur Wissenschaftsgeschichte, EarlyView.
In 2019 I started analyzing a large set of “race cards” preserved in the German Federal Archives (Bundesarchiv). These cards document anthropometric measurements performed by SS experts during WWII in the territories occupied by the Nazi regime. Applying a big data approach, my goal was to use those cards to study the inner dynamics of the racial ...
Amir Teicher
wiley   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Food‐solicitation displays in nestling birds: still begging for answers

Biological Reviews, EarlyView.
ABSTRACT Nestling begging is a key model for understanding animal communication and parent–offspring conflict. Dynamic begging displays are often interpreted as costly, honest signals of need, with honesty maintained by viability costs, as proposed in Godfray's influential signalling model.
Daniel Parejo‐Pulido, Tomás Redondo
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The performance of 11 fingertip pulse oximeters during hypoxemia in healthy human participants with varied, quantified skin pigmentResearch in context

EBioMedicine
Summary: Background: Fingertip pulse oximeters are widely available, inexpensive, and commonly used to make clinical decisions in many settings. Device performance is largely unregulated and poorly characterised, especially in people with dark skin ...
Gregory Leeb, Isabella Auchus, Tyler Law, Philip Bickler, John Feiner, Shamsudini Hashi, Ellis Monk, Elizabeth Igaga, Michael Bernstein, Yu Celine Chou, Caroline Hughes, Deleree Schornack, Jenna Lester, Kelvin Moore, Jr., Olubunmi Okunlola, Jana Fernandez, Leonid Shmuylovich, Michael Lipnick   +17 more
doaj   +1 more source

Photogrammetric Reconstruction of 3D Human Anatomical Structures and Augmented Reality via Smartphone Technology

Clinical Anatomy, EarlyView.
ABSTRACT Limited access to cadavers necessitates the availability of digital resources for anatomy education. Smartphone‐based photogrammetry offers a promising solution for creating three‐dimensional (3D) and augmented reality (AR) models. This study compared two mobile photogrammetry applications (Qlone and Polycam) that have been used in modern ...
Sarita Phukwantong, Paphawarin Ma‐imjai, Benrita Jitaree, Athinan Prommahom   +3 more
wiley   +1 more source

Phenolic‐Associated Dietary Fiber Ingredients From Agro‐Industrial Residues: Processing‐Dependent Identity and Food‐Grade Translation

ChemFoodChem, EarlyView.
Agro‐industrial residues contain dietary fiber and phenolics, but coexistence alone does not establish a phenolic‐bound ingredient. Processing‐dependent identity is verified through fraction‐specific analysis and common‐basis mass balance. Food‐grade translation requires final‐product performance, sensory acceptance, safety, and claim‐matched ...
Yitong Niu, Ireland LaBass, Sicheng Wang, Cheu Peng Leh, Ting Han   +4 more
wiley   +1 more source

Sequential Pressurized Liquid Extraction of Food Matrices: Fractionation, Selectivity, and Scale‐Up

ChemFoodChem, EarlyView.
Sequential pressurized liquid extraction separates food‐processing side streams into chemically distinct fractions by changing solvent polarity and operating conditions across stages. Lipophilic and phenolic compounds are recovered selectively, while co‐extraction is reduced.
Derya Ozalp Unal
wiley   +1 more source

Scale‐down before you scale‐up: Organic electronic materials scaled at Xerox Research Centre of Canada

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Organic electronics have emerged as a key class of functional materials for organic light‐emitting diodes (OLEDs), organic photovoltaics (OPVs), organic field‐effect transistors (OFETs), sensors, and printed electronics. However, commercialization remains dependent on the ability to reproducibly synthesize and manufacture high‐performance ...
Marko D. Saban, Benoît H. Lessard
wiley   +1 more source