Results 71 to 80 of about 15,177,173 (309)

Vascular responses of the extremities to transdermal application of vasoactive agents in Caucasian and African descent individuals [PDF]

, 2015
This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 04/04/2015, available online: https://doi.org/10.1007/s00421-015-3164-2 The accepted version of the publication may differ from the final ...
AC Shore, Army Medical surveillance activity, AT Koutsavlis, B Endrich, B Waeber, BJ Kim, C Cardillo, C Cardillo, CC Ungley, CC Ungley, Clare M. Eglin, CM Stein, CM Stein, CR Anderson, CS Thompson-Torgerson, D Bylund, D Miller, DA Rosenbaum, DF Kahn, DL Feairheller, DS Jones, DW DeGroot, E Clark, E Mata-Greenwood, FSC Golden, GA Conway, HA Daanen, HC Parkington, HP Rang, J Gainer, J Jia, J Jia, J Lundberg, James R. House, JE Burgess, JE Ramsay, JM Johnson, JP Noon, K Hope, K Komori, K Sauerstein, KK Griendling, KW Russell, L Ekenvall, L Kalinowski, LA Holowatz, LA Holowatz, M Honda, M Roustit, M Schmelz, M Shibasaki, MA Chotani, MA Chotani, MA Hashmi, Matthew J. Maley, ME Pueyo, Michael J. Tipton, MJ Easter, MJ Maley, MS Taylor, N Melikian, O Wilson, RF Furchgott, RG Hendry, RT Grant, RT Grant, SJ Duffy, SJ Morris, SJ Sarnoff, SR Bailey, T Lewis, TJ Cleophas, TM Mäkinen, WH Candler   +73 more
core   +4 more sources

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

New Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini, I. Magouras, C. Chapuis‐Taillard, O. Clerc, E. Masserey, G. Peduto, O. Péter, S. Schaerrer, G. Schuepbach, G. Greub   +9 more
wiley   +1 more source

Phenotypic continuum of NFU1‐related disorders

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022
Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov, Maha S. Zaki, Tracy Lau, Sambuddha Sen, Reza Azizimalamiri, Mina Zamani, Gözde Yeşil Sayin, Taru Hilander, Stephanie Efthymiou, Viorica Chelban, Ruth Brown, Kyle Thompson, Maria Irene Scarano, Jaya Ganesh, Kairgali Koneev, Ismail Musab Gülaçar, Richard Person, Dinara Sadykova, Yerdan Maidyrov, Tahereh Seifi, Aizhan Zadagali, Geneviève Bernard, Katrina Allis, Houda Zghal Elloumi, Amanda Lindy, Ehsan Taghiabadi, Sumit Verma, Rachel Logan, Brian Kirmse, Renkui Bai, Shaimaa M. Khalaf, Mohamed S. Abdel‐Hamid, Alireza Sedaghat, Gholamreza Shariati, Mahmoud Issa, Jawaher Zeighami, Hasnaa M. Elbendary, Garry Brown, Robert W. Taylor, Hamid Galehdari, Joseph J. Gleeson, Christopher J. Carroll, James A. Cowan, Andres Moreno‐De‐Luca, Henry Houlden, Reza Maroofian   +45 more
wiley   +1 more source

The Use of Matriderm and Autologous Skin Graft in the Treatment of Full Thickness Skin Defects

Archives of Plastic Surgery, 2014
Background For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes resulting from scars,
Jang Hwan Min, In Sik Yun, Dae Hyun Lew, Tai Suk Roh, Won Jai Lee   +4 more
doaj   +1 more source

Assessment of patch test results carried out during ten years in a city in southern Brazil [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: Contact dermatitis affects up to 20% of the population. Patch testing for contact allergy may be needed to confirm the diagnosis. Objectives: To describe and discuss the results of patch tests performed in a city in southern Brazil ...
Mariane Corrêa-Fissmer, Cintia Camila Dalazen, Bárbara Piacentini Ferreira, Betine Pinto Moehlecke Iser   +3 more
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

A Narrative Review on Evaluation of Causal Drug in Cutaneous Drug Eruptions: Challenges, Current State, and the Path Ahead

International Journal of Advanced Medical and Health Research
The diagnosis of cutaneous drug reactions is challenging, particularly when it involves the identification of the culprit drug. This exercise is, however, essential, as re-prescription of the offending drug is harmful to the patient while holding back an
Sivaranjini Ramassamy
doaj   +1 more source

Peri-Operative Anaphylaxis—An Investigational Challenge

Frontiers in Immunology, 2019
Patients with suspected peri-operative anaphylaxis (POP) require thorough investigation to identify underlying trigger(s) and enable safe anesthesia for subsequent surgery. The changing epidemiology of POP has been striking.
Siraj A. Misbah, Mamidipudi Thirumala Krishna, Mamidipudi Thirumala Krishna   +2 more
doaj   +1 more source