Results 31 to 40 of about 497,473 (285)
DA HISTÓRIA DO PENSAMENTO POLÍTICO À TEORIA POLÍTICA HISTÓRICA: VARIAÇÕES DA HERMENÊUTICA DO CONFLITO DE QUENTIN SKINNER [PDF]
Lua Nova: Revista de Cultura e Política, 2017 Resumo Visando a apresentação de um caso exemplar da abordagem histórica da teoria política, este artigo examina momentos decisivos da trajetória intelectual de Quentin Skinner, de suas primeiras publicações às mais recentes. Observa-se que, com o passar
Ricardo Silva
doaj +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Análise funcional do comportamento
Estudos de Psicologia (Campinas)A principal preocupação do analista comportamental é com o uso de unidades funcionais enquanto realizando uma análise do comportamento. As influências que levaram a essa postura são analisadas: um modelo de ciência das ciências naturais, um modelo ...
Maria Amélia Matos
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The type of Copaeodes chromis Skinner, 1919 (Lepidoptera: Hesperiidae: Hesperiinae) [PDF]
, 2009 The holotype of Copaeodes chromis Skinner, 1919 (Lepidoptera: Hesperiidae), housed at the Carnegie Museum of Natural History, is a typical specimen of Zariaspes mythecus Godman ...
Austin, George T., Warren, Andrew D.
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Definição, Tipos e Funções de Regra: Uma Interpretação da Obra de B. F. Skinner
Psicologia: Teoria e Pesquisa, 2017 RESUMO Este artigo tem por objetivo esclarecer a posição de B. F. Skinner sobre a definição, os tipos e as funções de regras no controle do comportamento humano.
Dante Marino Malavazzi +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Skinner’s Concept of Efficient Behavior
Interação em Psicologia, 2009 This essay presents the results of an analysis of Skinnerian texts, developed with the aim of making explicit the criteria with which Skinner uses the term efficient to qualify behaviors.
Ieda Maria Bertola Mazzo +1 more
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