Results 51 to 60 of about 108,939 (230)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Skid Skinner on Motorcycle

open access: yes
Skid Skinner (Hector Skinner), speedway and Wall of Death rider, seated on a Douglas motorcycle, 1928.
Skinner, Alma
core   +1 more source

Opvoedkundige Tegnologie / Educational Technology: Geprogrammeerde onderrig: Skinner en Crowder se bydraes

open access: yesScientia Militaria, 2012
The article: Programmed Instruction, The Contribution of Skinner and Crowder discusses exactly what is meant by the term Programmed Instruction, and the contribution made by Skinner and Crowder in particular are analysed.
U. Bouwer
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Um diálogo entre um cristão ortodoxo e um behaviorista radical

open access: yesPsicologia: Ciência e Profissão
Este artigo discute a religião através de um diálogo entre dois sujeitos fictícios: Tommaso, um behaviorista radical e defensor da idéia skinneriana de que a religião não se diferencia de outras formas de controle, e Gottlieb, um cristão ortodoxo e ...
Tyffanne Serra Paraná Rodrigues   +1 more
doaj  

Fronteiras entre análise do comportamento e fisiologia: Skinner e a temática dos eventos privados Boundaries between behavior analysis and physiology: Skinner and the issue of private events

open access: yesPsicologia: Reflexão e Crítica, 2000
O presente estudo examinou referências de B. F. Skinner à fisiologia em textos sobre eventos privados, com o objetivo de identificar elementos para uma demarcação mais precisa das relações entre análise do comportamento e fisiologia.
Emmanuel Zagury Tourinho   +2 more
doaj   +1 more source

S Skinner and Miss Alma

open access: yes, 2004
Publicity postcard for Skid Skinner (Hector Skinner) and Miss Alma (Alma Morley, married in 1941 to become Skid Skinner) showing them riding the Wall of ...
Skinner, Alma
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

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