Results 31 to 40 of about 108,939 (230)

“A Matter of Chance”: An Epistemological Interpretation of Chance in Radical Behaviorism [PDF]

Psicologia: Teoria e Pesquisa
The concept of chance cited by B. F. Skinner was not subject to a detailed examination to elucidate changes in his explanatory system. This article explains and discusses the meanings of chance identified in the author’s texts.
Christian Silva dos Reis, Carolina Laurenti   +1 more
doaj   +4 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

O Besouro na Caixa de Skinner, [PDF]

Psicologia: Teoria e Pesquisa
Resumo A literatura tem indicado algumas aproximações entre as propostas de Skinner e Wittgenstein, como, por exemplo, a crítica às concepções tradicionais de linguagem psicológica.
Luiza Bacchi Dourado, Carlos Eduardo Lopes, Henrique Mesquita Pompermaier   +2 more
doaj   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hukuman dalam Pendidikan : Studi Komparatif Pemikiran Abdullah Nasih ‘Ulwan dan B.F. Skinner

At-Tarbawi, 2017
This study is based on the phenomenon of the cases number of punishment abuse in education. Punishment has become a favorite treatment chosen by teachers to control students, though not all educators choose it becomes habit.
Ahmad Minan Zuhri
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

O contextualismo linguístico na história do pensamento político: Quentin Skinner e o debate metodológico contemporâneo

Dados: Revista de Ciências Sociais, 2010
Dans cet article, on souhaite situer et examiner le débat méthodologique proposé par l'École de Cambridge au sujet de l'histoire de la pensée politique dans les quatre dernières décennies, tout en insistant sur les positions de Quentin Skinner et les ...
Ricardo Silva
doaj   +1 more source