Results 71 to 80 of about 108,939 (230)

Notas sobre o Behaviorismo de ontem e de hoje Remarks on former and current Behaviorism

open access: yesPsicologia: Reflexão e Crítica, 2011
Este artigo busca oferecer algumas referências históricas sobre as origens e desenvolvimentos da Psicologia behaviorista. O artigo parte das contribuições de Watson, destacando seu afastamento do modo causal selecionista, inaugurado na Psicologia por ...
Emmanuel Zagury Tourinho
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

S Skinner and Miss Alma

open access: yes
Publicity postcard for Skid Skinner (Hector Skinner) and Miss Alma (Alma Morley, married in 1941 to become Skid Skinner) showing them riding the Wall of ...
Skinner, Alma
core   +1 more source

Operant Conditioning in Education

open access: yesCanadian Journal of Education, 1976
L'auteur fait l'analyse de la conception de B. F. Skinner sur la relation qui existe entre le conditionnement opérant et les exigences rationnelles de notre idéal pédagogique.
A.C. Kazepides
doaj   +2 more sources

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

The impact of displacement on disabled, injured and older Syrian refugees

open access: yesForced Migration Review, 2014
In contexts of displacement it is critical to recognise that some groups in the population may require specific attention. Awareness of these needs has major consequences for the types of services required, and the way they are delivered.
Marcus Skinner
doaj  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Explicação e descrição no Behaviorismo radical: identidade ou dicotomia?

open access: yesPsicologia: Teoria e Pesquisa
Este artigo examina uma inconsistência na proposta skinneriana com respeito às relações entre explicação e descrição. Em alguns momentos, Skinner identifica explicação e descrição, comprometendo-se com a máxima machiana " explicar é descrever" .
Carolina Laurenti, Carlos Eduardo Lopes
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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