Results 61 to 70 of about 39,489 (265)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Um dos aspectos mais interessantes e polêmicos da obra de B. F. Skinner é sua interpretação sobre a evolução das culturas. De acordo com o autor, as conseqüências de práticas culturais retroagem sobre as culturas, no sentido de aumentar ou diminuir suas ...
Alexandre Dittrich
doaj +1 more source
In dealing with Skinner, we are concerned with a theorist who now espouses no theory, a systematist whose system is still developing, and a constructive thinker some of whose most important contributions have been those of a critic. In the course of his writings, Skinner has presented the results of a comprehensive experimental program, and elaborated
openaire +2 more sources
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Notas sobre o Behaviorismo de ontem e de hoje Remarks on former and current Behaviorism
Este artigo busca oferecer algumas referências históricas sobre as origens e desenvolvimentos da Psicologia behaviorista. O artigo parte das contribuições de Watson, destacando seu afastamento do modo causal selecionista, inaugurado na Psicologia por ...
Emmanuel Zagury Tourinho
doaj +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Ideas políticas e historia intelectual
A propósito de Quentin Skinner, Reason and Rhetoric in the Philosophy of Hobbes, Cambridge, Cambridge University Press, 1996, 437 páginas, y Quentin Skinner, Liberty before Liberalism, Cambridge, Cambridge University Press, 1998, 142 páginas.
Elías José Palti
doaj
Rhetorical and Temporal Perspectives on Conceptual Change
Theses on Quentin Skinner and Reinhart ...
Kari Palonen
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Skinner was the most influential American psychologist, behaviourist, author, inventor, and social philosopher. He is regarded as father of operant conditioning. He is famous for his research on schedules of reinforcement by using animals in Skinner box.
Vivaswan Boorla
doaj

