Results 61 to 70 of about 1,113 (145)
Molecular Features of Glioma Determined and Validated Using Combined TCGA and GTEx Data Analyses
Frontiers in Oncology, 2021 Gliomas are among the most common intracranial tumors which originated from neuroepithelial cells. Increasing evidence has revealed that long noncoding RNA (lncRNA)-microRNA (miRNA)-mRNA module regulation and tumor-infiltrating immune cells play ...
Zijiang Yang +3 more
doaj +1 more source
Gene expression and functional annotation of the human and mouse choroid plexus epithelium [PDF]
, 2013 Background: The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles and produces the cerebrospinal fluid (CSF), which is crucial for brain homeostasis.
Bergen, A.A.B. (Arthur) +7 more
core +1 more source
A study of incidence, causative factors, symptoms, and prognosis in epilepsy with onset in the first two years of life [PDF]
, 2022 Background: The motivation to start this thesis work came from the meetings with infants just having presented with epileptic seizures and from speaking to their parents. I found two issues to be particularly urgent.
Stödberg, Tommy
core +1 more source
Identification of potential biomarkers and candidate small molecule drugs in glioblastoma
Cancer Cell International, 2020 Background and aims Glioblastoma (GBM) is a common and aggressive primary brain tumor, and the prognosis for GBM patients remains poor. This study aimed to identify the key genes associated with the development of GBM and provide new diagnostic and ...
Wei-cheng Lu +5 more
doaj +1 more source
Prognostic significance of AP-2α/γ targets as cancer therapeutics
Scientific Reports, 2022 Identifying genes with prognostic importance could improve cancer treatment. An increasing number of reports suggest the existence of successful strategies based on seemingly “untargetable” transcription factors.
Damian Kołat +3 more
doaj +1 more source
Epilepsia, Volume 66, Issue 8, Page 2966-2979, August 2025.Abstract Objective A large proportion of pediatric epilepsies have an underlying genetic etiology. Limited studies have explored the efficacy of whole genome sequencing (WGS) in a clinical setting. Our academic–clinical center implemented clinical whole exome sequencing (WES) in 2014, then transitioned to WGS from 2015.
Olivia J. Henry +10 more
wiley +1 more source
Generation and Characterization of the Cation-Chloride Cotransporter KCC2 Hypomorphic Mouse [PDF]
, 2006 The cation-Cl- cotransporter (CCC) family comprises of Na+-Cl- cotransporter (NCC), Na+-K+-2Cl- cotransporters (NKCC1-2), and four K+-Cl- cotransporters (KCC1-4).
Tornberg, Janne
core
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes [PDF]
, 2007 Background Melanoma is the major cause of skin cancer deaths and melanoma incidence doubles every 10 to 20 years. However, little is known about melanoma pathway aberrations.
Kuo Ping Chiu +62 more
core +2 more sources
Journal of Cellular and Molecular MedicineAbstractHepatocellular carcinoma (HCC) presents a persistent challenge to conventional therapeutic approaches. SLC12A5 is implicated in an oncogenic capacity and facilitates the progression of cancer. The objective of this investigation is to scrutinize the inhibitory effects of borax on endoplasmic reticulum (ER)‐stress and apoptosis mediated by ...
Ceyhan Hacioglu, Didem Oral
openaire +3 more sources
The role of hypoxia in glioblastoma invasion [PDF]
, 2017 Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 to 17 months. The current treatment for GBM involves tumor resection surgery
Frederick +8 more
core +3 more sources