Results 41 to 50 of about 1,113 (145)
BMC Cardiovascular Disorders, 2023 Aim To evaluate the expression profile of long non-coding RNAs (lncRNAs) in calcific aortic valve disease (CAVD) and explore their potential mechanism of action.
Guang-Yuan Song +8 more
doaj +1 more source
Frontiers in Genetics, 2021 Pathological neovascularization in choroid, a leading cause of blindness, is a characteristic of many fundus diseases, such as diabetic retinopathy and age-related macular degeneration.
Jie Jia +11 more
doaj +1 more source
Common Ribs of Inhibitory Synaptic Dysfunction in the Umbrella of Neurodevelopmental Disorders
, 2018 The term neurodevelopmental disorder (NDD) is an umbrella term used to group together a heterogeneous class of disorders characterized by disruption in cognition, emotion, and behavior, early in the developmental timescale.
Hines, Rochelle M. +2 more
core +2 more sources
Gene panel analysis for nonsyndromic cryptogenic neonatal/infantile epileptic encephalopathy [PDF]
, 2017 published_or_final_versio
Fung, CW, Kwong, KY, Wong, CNV
core +1 more source
Arteannuin B Inhibits NSCLC Cells via Regulating miR‐194‐3p/CLDN2 Axis
Cancer Medicine, Volume 15, Issue 4, April 2026.Arteannuin B (Art B), a sesquiterpene lactone from Artemisia annua, upregulates miR‐194‐3p, which directly targets two conserved sites (nt 358–365 and 1232–1238) in the CLDN2 3′ UTR. This triggers mRNA decay and blocks translation, suppressing CLDN2 expression.
Ting‐Sha He +9 more
wiley +1 more source
Cells, 2020 Androgen deprivation therapy (ADT) is standard-of-care for advanced-stage prostate cancer, and enzalutamide (Xtandi®, Astellas, Northbrook, IL, USA), a second generation antiandrogen, is prescribed in this clinical setting.
Shiv Verma +3 more
doaj +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 8, Page 168-189, December 2025.ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino +8 more
wiley +1 more source
Common Transcriptional Signatures in Brain Tissue from Patients with HIV-Associated Neurocognitive Disorders, Alzheimer’s Disease, and Multiple Sclerosis [PDF]
, 2012 HIV-Associated Neurocognitive Disorders (HAND) is a common manifestation of HIV infection that afflicts about 50 % of HIV-positive individuals. As people with access to antiretroviral treatments live longer, HAND can be found in increasing segments of ...
Alejandra Borjabad, David J. Volsky
core +1 more source
DNA Methylation-based Diagnostic and Prognostic Biomarkers for Glioblastoma
Cell Transplantation, 2020 Glioblastomas are the most common primary central nervous system malignancy tumor in adults. Glioblastoma patients have poor prognosis, with an average survival period of approximately 14 mo after diagnosis.
Yunliang Tang +3 more
doaj +1 more source
Habenula as a possible target for treatment-resistant depression phenotype in Wistar Kyoto rats [PDF]
, 2022 The mechanisms of treatment-resistant depression (TRD) are not clear and are difficult to study. An animal model resembling human TRD is the Wistar Kyoto rat strain.
Dziedzicka-Wasylewska, Marta +6 more
core +2 more sources