Cancer Management and Research, 2019 Hui-Feng Gao,1,2,* Lian-Yu Chen,1,2,* Chien-Shan Cheng,1,2 Hao Chen,1,2 Zhi-Qiang Meng,1,2 Zhen Chen1,21Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, People’s Republic of China; 2Department of Integrative ...
Zhen Chen +2 more
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Journal of Ginseng Research, 2022 Background: Ginsenoside Rd is a natural compound with promising neuroprotective effects. However, the underlying mechanisms are still not well-understood. In this study, we explored whether ginsenoside Rd exerts protective effects on cerebral endothelial
Suping Li +5 more
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JPMA the Journal of the Pakistan Medical AssociationCongenital glucose-galactose malabsorption (GGM) is an exceedingly uncommon autosomal recessive metabolic state defined by persistent diarrhoea along with serious dehydration.
Murat Tutanç, Hanïfe Aysegul Arsoy
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Protective effect of antidiabetic drugs against male infertility: evidence from Mendelian randomization [PDF]
Diabetology & Metabolic SyndromeBackground The global prevalence of diabetes has been steadily increasing, with a growing number of younger individuals being affected. Over recent decades, various antidiabetic drugs have been repurposed for treating conditions beyond diabetes. However,
Yuqi Li +6 more
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Congenital Glucose–Galactose Malabsorption Presenting as Hypertriglyceridemia and Medullary Nephrocalcinosis [PDF]
Pediatric ReportsA 4-month-old male child was admitted with failure to thrive, persistent osmotic diarrhea, and presence of multiple metabolic abnormalities, which included hypertriglyceridemia, hypercholesterolemia, hypercalcemia, and medullary nephrocalcinosis.
Malika Goel, Renu Suthar, Lesa Dawman
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The mechanism of gut microbiota in septic cardiomyopathy based on the bulk transcriptome and Mendelian randomization analysis [PDF]
Frontiers in ImmunologyBackgroundSeptic cardiomyopathy (SCM) is one of the most common and serious complications of sepsis. Earlier research has identified reciprocal regulation between SCM and gut microbiota (GM), but the mechanistic basis of GM in SCM development remains ...
Yuxia Tao +5 more
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Efficient Synthesis of Glucovanillin and Elucidation of Its Molecular Mechanisms in Ameliorating T2DM via Core Target Modulation and α-Glucosidase Inhibition [PDF]
MoleculesThis study focuses on the synthesis of glucovanillin mediated by UGT109A1 and its mechanism against Type 2 Diabetes Mellitus (T2DM). Recombinant UGT109A1 successfully synthesized glucovanillin from vanillin using UDP-Glc as the sugar donor.
Huanyu Zhang +5 more
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Effects of Raffinose on Growth Performance, Intestinal Function-Related Genes, and Cecal Microbiota in Broilers Fed Low Soybean Meal Diets [PDF]
AnimalsThis study investigated the effects of a low soybean meal (SBM) diet and its supplementation with graded levels of raffinose on the growth performance, expression of genes related to nutrient transport and intestinal function, and cecal microbiota of ...
Xiang Lan +11 more
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The effects of β-caryophyllene on butyrate utilization and metabolism in Caco-2 cells [PDF]
Scientific ReportsΒ-caryophyllene (BCP) is a plant compound that may exert bioactive effects on intestinal epithelial cell (IEC) function, including metabolism of butyrate, which is important for regulating cellular functions. The goal of this study was to investigate the
H. Scroggins +4 more
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Polystyrene microplastics compromise intestinal health and reduce growth and slaughter performance of Chahua chicken No. 2 [PDF]
Frontiers in MicrobiologyMicroplastics are ubiquitous in livestock settings and raise increasing concern, yet studies on their effects on poultry intestinal health and gut microbiota, particularly in native Chinese breeds, are still scarce. Chahua chicken No.
Kun Wang +14 more
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