Results 51 to 60 of about 707,629 (374)

Identification of Trypanosome proteins in plasma from African sleeping sickness patients infected with T. b. rhodesiense. [PDF]

open access: yesPLoS ONE, 2013
Control of human African sleeping sickness, caused by subspecies of the protozoan parasite Trypanosoma brucei, is based on preventing transmission by elimination of the tsetse vector and by active diagnostic screening and treatment of infected patients ...
Brett A Eyford   +4 more
doaj   +1 more source

The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda.

open access: yes, 2001
BACKGROUND: Sleeping sickness, caused by two trypanosome subspecies, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, is a parasitic disease transmitted by the tsetse fly in sub-Saharan Africa.
Coleman, PG   +5 more
core   +1 more source

Closing in on a new treatment for sleeping sickness [PDF]

open access: yes, 2014
A chemoproteomics approach has been employed to identify a kinase that could be used as a druggable target in efforts to develop new treatments for African sleeping ...
Clardy, Jon, Derbyshire, Emily R
core   +1 more source

Implications of Heterogeneous Biting Exposure and Animal Hosts on Trypanosomiasis brucei gambiense Transmission and Control. [PDF]

open access: yesPLoS Computational Biology, 2015
The gambiense form of sleeping sickness is a neglected tropical disease, which is presumed to be anthroponotic. However, the parasite persists in human populations at levels of considerable rarity and as such the existence of animal reservoirs has been ...
Chris M Stone, Nakul Chitnis
doaj   +1 more source

Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle

open access: yesMicroorganisms, 2022
Parasitic protists cause some of the most well-known human and animal diseases such as malaria, toxoplasmosis, amoebic meningitis, sleeping sickness, leishmaniosis, and diarrheal illness of protozoan origin (e [...]
Iva Kolářová   +2 more
doaj   +1 more source

Adding tsetse control to medical activities contributes to decreasing transmission of sleeping sickness in the Mandoul focus (Chad)

open access: yesPLoS Neglected Tropical Diseases, 2017
Background Gambian sleeping sickness or HAT (human African trypanosomiasis) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by riverine species of tsetse.
Mahamat Hisséne Mahamat   +16 more
semanticscholar   +1 more source

Tsetse Control and the Elimination of Gambian Sleeping Sickness

open access: yesPLoS Neglected Tropical Diseases, 2016
Sleeping sickness, or Human African Trypanosomiasis (HAT), is caused by two distinct parasites. In East and Southern Africa, Trypanosoma brucei rhodesiense causes the Rhodesian form of the disease (about 2% of all reported cases [1]). In Central and West
M. Lehane   +11 more
semanticscholar   +1 more source

Trypanosoma brucei Invasion and T-Cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes

open access: yesPLoS Neglected Tropical Diseases, 2016
Background The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has been ...
Claudia Laperchia   +8 more
semanticscholar   +1 more source

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