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Identification of Trypanosome proteins in plasma from African sleeping sickness patients infected with T. b. rhodesiense. [PDF]
Control of human African sleeping sickness, caused by subspecies of the protozoan parasite Trypanosoma brucei, is based on preventing transmission by elimination of the tsetse vector and by active diagnostic screening and treatment of infected patients ...
Brett A Eyford+4 more
doaj +1 more source
The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda.
BACKGROUND: Sleeping sickness, caused by two trypanosome subspecies, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, is a parasitic disease transmitted by the tsetse fly in sub-Saharan Africa.
Coleman, PG+5 more
core +1 more source
Closing in on a new treatment for sleeping sickness [PDF]
A chemoproteomics approach has been employed to identify a kinase that could be used as a druggable target in efforts to develop new treatments for African sleeping ...
Clardy, Jon, Derbyshire, Emily R
core +1 more source
Implications of Heterogeneous Biting Exposure and Animal Hosts on Trypanosomiasis brucei gambiense Transmission and Control. [PDF]
The gambiense form of sleeping sickness is a neglected tropical disease, which is presumed to be anthroponotic. However, the parasite persists in human populations at levels of considerable rarity and as such the existence of animal reservoirs has been ...
Chris M Stone, Nakul Chitnis
doaj +1 more source
Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle
Parasitic protists cause some of the most well-known human and animal diseases such as malaria, toxoplasmosis, amoebic meningitis, sleeping sickness, leishmaniosis, and diarrheal illness of protozoan origin (e [...]
Iva Kolářová+2 more
doaj +1 more source
Background Gambian sleeping sickness or HAT (human African trypanosomiasis) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by riverine species of tsetse.
Mahamat Hisséne Mahamat+16 more
semanticscholar +1 more source
Tsetse Control and the Elimination of Gambian Sleeping Sickness
Sleeping sickness, or Human African Trypanosomiasis (HAT), is caused by two distinct parasites. In East and Southern Africa, Trypanosoma brucei rhodesiense causes the Rhodesian form of the disease (about 2% of all reported cases [1]). In Central and West
M. Lehane+11 more
semanticscholar +1 more source
Background The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has been ...
Claudia Laperchia+8 more
semanticscholar +1 more source