Results 31 to 40 of about 140,774 (244)

Detection of trypanosomes in small ruminants and pigs in western Kenya: important reservoirs in the epidemiology of sleeping sickness? [PDF]

, 2005
Background Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa and limits the full potential of agricultural development in the 36 countries where it is endemic.
Musa O Ng'ayo, Zablon K Njiru, Eucharia U Kenya, Njiru, Z.K., Ellie O Osir, Kenya, E.U., Masiga, D.K., Geoffrey M Muluvi, Osir, E.O., Muluvi, G.M., Daniel K Masiga, Ng'ayo, M.O.   +11 more
core   +1 more source

Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues [PDF]

, 2008
Glycosylphosphatidylinositol (GPI)-anchored proteins are abundant in the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness in humans and the related disease Nagana in cattle, and disruption of GPI biosynthesis is ...
Nikolaev, Andrei V., Crossman, Arthur, Ferguson, Michael A. J., Ferguson, Michael A. J.; id_orcid, Yashunsky, Dmitry V., Urbaniak, Michael D.   +5 more
core   +5 more sources

Factors affecting the propensity of tsetse flies to enter houses and attack humans inside : increased risk of sleeping sickness in warmer climates [PDF]

, 2013
Background: Sleeping sickness, or human African trypanosomiasis, is caused by two species of Trypanosoma brucei that are transmitted to humans by tsetse flies (Glossina spp.) when these insects take a bloodmeal.
Vale Glyn A., Hall, D. R., David R Hall, John W Hargrove, Torr, Stephen, Hall David R., Clement Mangwiro, Mangwiro, Clement, Vale, Glyn A., Glyn A Vale, Hargrove John W., Chamisa, Andrew, Hall, David R., Mangwiro Clement, Hargrove, John W., Chamisa Andrew, Torr Stephen J., Stephen J Torr, Andrew Chamisa, Torr, Stephen J.   +19 more
core   +2 more sources

Identification of Trypanosome proteins in plasma from African sleeping sickness patients infected with T. b. rhodesiense. [PDF]

PLoS ONE, 2013
Control of human African sleeping sickness, caused by subspecies of the protozoan parasite Trypanosoma brucei, is based on preventing transmission by elimination of the tsetse vector and by active diagnostic screening and treatment of infected patients ...
Brett A Eyford, Rushdy Ahmad, John C Enyaru, Steven A Carr, Terry W Pearson   +4 more
doaj   +1 more source

Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle

Microorganisms, 2022
Parasitic protists cause some of the most well-known human and animal diseases such as malaria, toxoplasmosis, amoebic meningitis, sleeping sickness, leishmaniosis, and diarrheal illness of protozoan origin (e [...]
Iva Kolářová, Isabelle Florent, Andrea Valigurová   +2 more
doaj   +1 more source

Efficacy and safety of pafuramidine versus pentamidine maleate for treatment of first stage sleeping sickness in a randomized, comparator-controlled, international phase 3 clinical trial [PDF]

, 2016
Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration.
Carol A. Olson (1807531), Mintwo, Alain Fukinsia, Deo, Gratias Kambau Manesa, Sonja C. Bernhard, Bilenge, Constantin Miaka Mia, Patrick Mangoni N'tombe, Pierre Nsele Mutantu (1807651), Gabriele Pohlig, Patrick Mangoni N’tombe (1807627), Sonja C Bernhard, Alain Fukinsia Mintwo, N'tombe, Patrick Mangoni, N’tombe, Patrick Mangoni, Stephen Macharia (1807624), Kuikumbi, Florent Mbo, Mpanya, Alain, Richard R. Tidwell, Alain Mpanya, Augustin Kayeye Munungi, Blum, Johannes, Gratias Kambau Manesa Deo, Alain Fukinsia Mintwo (1807636), Gabriele Pohlig, Richard R Tidwell, Pierre Nsele Mutantu, Constantin Miaka Mia Bilenge, Gratias Kambau Manesa Deo (1807630), Patrick Mangoni N’tombe, Alfred Mpoo Mpoto, Bernhard, Sonja C., Augustin Kayeye Munungi (1807645), Tidwell, Richard R., Christian Burri (141244), Carol A Olson, Ndinga Dieyi Dituvanga, Sonja C. Bernhard (1807537), Ndinga Dieyi Dituvanga (1807648), Blaise Fungula Munungu, Burri, Christian, Munungu, Blaise Fungula, Olson, Carol A., Macharia, Stephen, Dituvanga, Ndinga Dieyi, Victor Kande Betu Ku Mesu, Constantin Miaka Mia Bilenge (1807513), Blaise Fungula Munungu (1807519), Mpoto, Alfred Mpoo, Christian Burri, Jose Ramon Franco, Jean-Pierre Fina Lubaki (1807546), Mutantu, Pierre Nsele, Franco, Jose Ramon, Johannes Blum, Lubaki, Jean-Pierre Fina, Gabriele Pohlig (267149), Pohlig, Gabriele, Jose Ramon Franco (1807639), Carol A. Olson, Mesu, Victor Kande Betu Ku, Alfred Mpoo Mpoto (1807534), Stephen Macharia, Alain Mpanya (267142), Amadeu Dala, Johannes Blum (141240), Dala, Amadeu, Munungi, Augustin Kayeye, Victor Kande Betu Ku Mesu (1807510), Florent Mbo Kuikumbi (1807633), Amadeu Dala (1807642), Richard R. Tidwell (148409), Florent Mbo Kuikumbi, Jean-Pierre Fina Lubaki   +71 more
core   +1 more source

Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis. [PDF]

, 2011
Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation ...
Francesco Checchi, Gerardo Priotto, Daniel Chandramohan, Checchi Francesco, Unni Karunakara, Priotto Gerardo, Checchi, F, Priotto, Gerardo, Priotto, G, Checchi, Francesco, Chappuis, F, Chandramohan, D, Chandramohan, Daniel, Karunakara Unni, François Chappuis, Karunakara, U, Karunakara, Unni, Chappuis, François, Chappuis François, Chandramohan Daniel   +19 more
core   +2 more sources

We Remember… Elders' Memories and Perceptions of Sleeping Sickness Control Interventions in West Nile, Uganda.

PLoS Neglected Tropical Diseases, 2016
The traditional role of African elders and their connection with the community make them important stakeholders in community-based disease control programmes.
Vanja Kovacic, Inaki Tirados, Johan Esterhuizen, Clement T N Mangwiro, Michael J Lehane, Stephen J Torr, Helen Smith   +6 more
doaj   +1 more source

Towards the Atlas of human African trypanosomiasis [PDF]

, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Cecchi Giuliano, Simarro Pere P, Fevre, Eric M., Mattioli, Raffaele C., Ruíz, J.A., Franco José R, Cecchi, Giuliano, Raffaele C Mattioli, Abdoulaye Diarra, Paone, M., José R Franco, Mattioli Raffaele C, Ruiz, Jose A., Diarra, A., Paone, Massimo, Diarra, Abdoulaye, Paone Massimo, Massimo Paone, Franco, Jose R., José A Ruiz, Diarra Abdoulaye, Eric M Fèvre, Simarro, Pere P., Pere P Simarro, Fèvre Eric M, Franco, J.R., Cecchi, G., Giuliano Cecchi, Ruiz José A   +28 more
core   +1 more source

Screening of Trypanosoma brucei gambiense in domestic livestock and tsetse flies from an insular endemic focus (Luba, Equatorial Guinea). [PDF]

, 2010
BACKGROUND: Sleeping sickness is spread over 36 Sub-Saharan African countries. In West and Central Africa, the disease is caused by Trypanosoma brucei gambiense, which produces a chronic clinical manifestation.
Abaga, Simón, Pedro Ndongo-Asumu, Ochando, Jordi, Ndong-Mabale Nicolás, Carmen García-Estébanez, Nicolás Ndong-Mabale, Ndong-Mabale, Nicolás, Agustín Benito, Carlos Cordon-Obras, Ndongo-Asumu, Pedro, Benito Agustín, García-Estébanez, Carmen, Cano, Jorge, Cordon-Obras, Carlos, Cano Jorge, Benito, Agustín, Cordon-Obras Carlos, Simón Abaga, Abaga Simón, Ndongo-Asumu Pedro, Jorge Cano, García-Estébanez Carmen   +21 more
core   +2 more sources