Results 31 to 40 of about 21,177 (293)

Factors affecting the propensity of tsetse flies to enter houses and attack humans inside : increased risk of sleeping sickness in warmer climates [PDF]

, 2013
Background: Sleeping sickness, or human African trypanosomiasis, is caused by two species of Trypanosoma brucei that are transmitted to humans by tsetse flies (Glossina spp.) when these insects take a bloodmeal.
Vale Glyn A., Hall, D. R., David R Hall, John W Hargrove, Torr, Stephen, Hall David R., Clement Mangwiro, Mangwiro, Clement, Vale, Glyn A., Glyn A Vale, Hargrove John W., Chamisa, Andrew, Hall, David R., Mangwiro Clement, Hargrove, John W., Chamisa Andrew, Torr Stephen J., Stephen J Torr, Andrew Chamisa, Torr, Stephen J.   +19 more
core   +1 more source

Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness. [PDF]

RSC Med Chem, 2020
African sleeping sickness is a potentially fatal neglected disease affecting sub-Saharan Africa. Highthroughput screening identified the thiazolyl-benzothiophenamide 1 to be active against the causative parasite, Trypanosoma brucei. This work establishes
Brown RW, Abdel-Megeed AM, Keller PA, Jones AJ, Sykes ML, Kaiser M, Baell JB, Avery VM, Hyland CJT.   +8 more
europepmc   +2 more sources

Identification of Trypanosome proteins in plasma from African sleeping sickness patients infected with T. b. rhodesiense. [PDF]

PLoS ONE, 2013
Control of human African sleeping sickness, caused by subspecies of the protozoan parasite Trypanosoma brucei, is based on preventing transmission by elimination of the tsetse vector and by active diagnostic screening and treatment of infected patients ...
Brett A Eyford, Rushdy Ahmad, John C Enyaru, Steven A Carr, Terry W Pearson   +4 more
doaj   +1 more source

Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle

Microorganisms, 2022
Parasitic protists cause some of the most well-known human and animal diseases such as malaria, toxoplasmosis, amoebic meningitis, sleeping sickness, leishmaniosis, and diarrheal illness of protozoan origin (e [...]
Iva Kolářová, Isabelle Florent, Andrea Valigurová   +2 more
doaj   +1 more source

Three drug combinations for late-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Uganda.

, 2006
OBJECTIVES: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Louga, Albino, Fogg Carole, Louga Albino, Ghabri, S, Piola, P, Piola, Patrice, Balasegaram, M, Checchi Francesco, Balasegaram, Manica, Priotto Gerardo, Louga, A, Checchi, F, Priotto, Gerardo, Priotto, G, Erphas, Olema, Checchi, Francesco, Ghabri, Salah, Erphas, O, Balasegaram Manica, Ghabri Salah, Erphas Olema, Fogg, C, Fogg, Carole, Piola Patrice   +23 more
core   +1 more source

Efficacy and safety of pafuramidine versus pentamidine maleate for treatment of first stage sleeping sickness in a randomized, comparator-controlled, international phase 3 clinical trial [PDF]

, 2016
Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration.
Carol A. Olson (1807531), Mintwo, Alain Fukinsia, Deo, Gratias Kambau Manesa, Sonja C. Bernhard, Bilenge, Constantin Miaka Mia, Patrick Mangoni N'tombe, Pierre Nsele Mutantu (1807651), Gabriele Pohlig, Patrick Mangoni N’tombe (1807627), Sonja C Bernhard, Alain Fukinsia Mintwo, N'tombe, Patrick Mangoni, N’tombe, Patrick Mangoni, Stephen Macharia (1807624), Kuikumbi, Florent Mbo, Mpanya, Alain, Richard R. Tidwell, Alain Mpanya, Augustin Kayeye Munungi, Blum, Johannes, Gratias Kambau Manesa Deo, Alain Fukinsia Mintwo (1807636), Gabriele Pohlig, Richard R Tidwell, Pierre Nsele Mutantu, Constantin Miaka Mia Bilenge, Gratias Kambau Manesa Deo (1807630), Patrick Mangoni N’tombe, Alfred Mpoo Mpoto, Bernhard, Sonja C., Augustin Kayeye Munungi (1807645), Tidwell, Richard R., Christian Burri (141244), Carol A Olson, Ndinga Dieyi Dituvanga, Sonja C. Bernhard (1807537), Ndinga Dieyi Dituvanga (1807648), Blaise Fungula Munungu, Burri, Christian, Munungu, Blaise Fungula, Olson, Carol A., Macharia, Stephen, Dituvanga, Ndinga Dieyi, Victor Kande Betu Ku Mesu, Constantin Miaka Mia Bilenge (1807513), Blaise Fungula Munungu (1807519), Mpoto, Alfred Mpoo, Christian Burri, Jose Ramon Franco, Jean-Pierre Fina Lubaki (1807546), Mutantu, Pierre Nsele, Franco, Jose Ramon, Johannes Blum, Lubaki, Jean-Pierre Fina, Gabriele Pohlig (267149), Pohlig, Gabriele, Jose Ramon Franco (1807639), Carol A. Olson, Mesu, Victor Kande Betu Ku, Alfred Mpoo Mpoto (1807534), Stephen Macharia, Alain Mpanya (267142), Amadeu Dala, Johannes Blum (141240), Dala, Amadeu, Munungi, Augustin Kayeye, Victor Kande Betu Ku Mesu (1807510), Florent Mbo Kuikumbi (1807633), Amadeu Dala (1807642), Richard R. Tidwell (148409), Florent Mbo Kuikumbi, Jean-Pierre Fina Lubaki   +71 more
core   +1 more source

SLEEPING SICKNESS: A DISCLAIMER. [PDF]

The Lancet, 1903
n ...
openaire   +2 more sources

Towards the Atlas of human African trypanosomiasis [PDF]

, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Cecchi Giuliano, Simarro Pere P, Fevre, Eric M., Mattioli, Raffaele C., Ruíz, J.A., Franco José R, Cecchi, Giuliano, Raffaele C Mattioli, Abdoulaye Diarra, Paone, M., José R Franco, Mattioli Raffaele C, Ruiz, Jose A., Diarra, A., Paone, Massimo, Diarra, Abdoulaye, Paone Massimo, Massimo Paone, Franco, Jose R., José A Ruiz, Diarra Abdoulaye, Eric M Fèvre, Simarro, Pere P., Pere P Simarro, Fèvre Eric M, Franco, J.R., Cecchi, G., Giuliano Cecchi, Ruiz José A   +28 more
core   +1 more source

We Remember… Elders' Memories and Perceptions of Sleeping Sickness Control Interventions in West Nile, Uganda.

PLoS Neglected Tropical Diseases, 2016
The traditional role of African elders and their connection with the community make them important stakeholders in community-based disease control programmes.
Vanja Kovacic, Inaki Tirados, Johan Esterhuizen, Clement T N Mangwiro, Michael J Lehane, Stephen J Torr, Helen Smith   +6 more
doaj   +1 more source

Estimates of the duration of the early and late stage of gambiense sleeping sickness

, 2008
Background: The durations of untreated stage 1 (early stage, haemo-lymphatic) and stage 2 (late stage, meningo-encephalitic) human African trypanosomiasis (sleeping sickness) due to Trypanosoma brucei gambiense are poorly quantified, but key to ...
Filipe, João AN, Haydon Daniel T, Filipe João AN, Chappuis, F., Checchi Francesco, Haydon, D.T., Checchi, F, Checchi, Francesco, Chandramohan, D, Chappuis, F, Chandramohan, Daniel, Filipe, J A N, Filipe, João A N., Haydon, Daniel T, Haydon, D T, Filipe, J.A., Haydon, Daniel T., Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +21 more
core   +1 more source