Results 41 to 50 of about 821,881 (278)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Presence of Calcium Lowers the Expansion of Bacillus subtilis Colony Biofilms
Microorganisms, 2017 Robust colony formation by Bacillus subtilis is recognized as one of the sessile, multicellular lifestyles of this bacterium. Numerous pathways and genes are responsible for the architecturally complex colony structure development.
Eisha Mhatre +5 more
doaj +1 more source
Evaluation of the effect of different points of orthodontic force application (A typodont study) [PDF]
Al-Rafidain Dental Journal, 2011 Aims: To determine the effect of different points of force application on dimensional positions and the ratio of space closure of maxillary canine using sliding mechanics.
Omar KhM Thiab +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Design sizing of cylindrical worm gearsets [PDF]
FME Transactions, 2020 A method for the design sizing task of cylindrical worm gearsets is presented that gives an estimate of the initial value of the normal module. Expressions are derived for the worm pitch diameter of integral and shell worms as well as for the active face
Osakue Edward E., Anetor Lucky
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Three-dimensional integral dry friction model for the motion of a rectangular body
Advanced Engineering Research, 2021 Introduction. A three-dimensional dry friction model in the interaction of a rectangular body and a horizontal rough surface is considered. It is assumed that there is no separation of the body from the horizontal surface.
M. S. Salimov, I. V. Merkuriev
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
3D numerical simulation of seismic failure of concrete gravity dams considering base sliding
Modelling in Civil Environmental Engineering, 2022 The sliding of dam base along dam-foundation rock interface during earthquake excitation can decrease the earthquake response of the dam. The present study reveals a numerical simulation of the seismic failure response for Oued Fodda concrete gravity dam,
DJAMEL Ouzandja, MOKHTAR Messaad
doaj +1 more source
The Sliding Singlet Mechanism with Gauge Mediated Supersymmetry Breaking [PDF]
, 1998 The sliding singlet mechanism is one of the most interesting solutions of the triplet-doublet splitting problem. We analyze this mechanism in the gauge mediated supersymmetry breaking scenario.
A. Anselm +40 more
core +2 more sources