Results 61 to 70 of about 910,363 (405)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Modeling and Lyapunov-designed based on adaptive gain sliding mode control for wind turbines [PDF]

, 2016
In this paper, modeling and the Lyapunov-designed control approach are studied for the Wind Energy Conversion Systems (WECS). The objective of this study is to ensure the maximum energy production of a WECS while reducing the mechanical stress on the ...
Boumediene, Larbi, Djamel Eddine Kerrouche, Kamel, Mezouar, Abdelkader, Van den Bossche, Alex   +3 more
core  

Sliding Mode Control of Two-Level Quantum Systems

, 2011
This paper proposes a robust control method based on sliding mode design for two-level quantum systems with bounded uncertainties. An eigenstate of the two-level quantum system is identified as a sliding mode.
Adamy, Altafini, Belavkin, Bolognani, Bonnard, Boscain, Bouten, Cui, Daoyi Dong, Doherty, Dong, Dong, Dong, Dong, Dong, Dong, Dowling, D’Alessandro, D’Alessandro, D’Helon, Facchi, Grivopoulos, Ian R. Petersen, Itano, James, Judson, Khaneja, Kirk, Kuang, LaSalle, Lee, Mabuchi, Mirrahimi, Mirrahimi, Misra, Nielsen, Nurdin, Nurdin, Pechen, Pravia, Qi, Rabitz, Romano, Stefanatos, Ticozzi, Utkin, van Handel, Vilela Mendes, Viola, Wang, Wang, Wang, Wiseman, Wiseman, Yamamoto, Yamamoto, Yanagisawa, Zhang, Zhang   +58 more
core   +1 more source

Sliding mode control for high-precision motion of a piezostage [PDF]

, 2007
In this paper, control of piezostage using sliding mode control (SMC) method is presented. Due to the fast dynamics of piezostage and since high accuracy is required the special attention is paid to avoid chattering.
Abidi, Khalid Seyed, Sabanovic, Asif, Şabanoviç, Asif   +2 more
core   +1 more source

Design and Control of a Quasi-Z Source Multilevel Inverter Using a New Reaching Law-Based Sliding Mode Control [PDF]

, 2022
Muhammad Rafiq, Abasin Ulasyar, Waqar Uddin, Haris Sheh Zad, Abraiz Khattak, Kamran Zeb   +5 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Fixed-Time-Convergent Sliding Mode Control with Sliding Mode Observer for PMSM Speed Regulation

Sensors
This paper focuses on the speed control of a permanent magnet synchronous motor (PMSM) for electric drives with model uncertainties and external disturbances.
Xin Zhang, Hongwen Li, Meng Shao
doaj   +1 more source

Sliding modes in power electronics and motion control [PDF]

, 2004
In the paper the general approach to motion control systems in the sliding mode framework is discussed in details. It has been shown that, due to the fact that a motion control system with n d.o.f may be mathematically formulated in a unique way as a ...
Sabanovic, Asif, Şabanoviç, Asif
core  

Depth control of autonomous underwater vehicle using discrete time sliding mode controller [PDF]

, 2019
This study presents a Discrete Time Sliding Mode Controller (DSMC) application on depth plane of Autonomous Underwater Vehicle (AUV). The main contribution on this work is an implementation of DSMC on NSP AUV II.
A. Jalil, Mohd Hafiz, Abdul Kadir, Herdawatie, Ngadengon, Rafidah, Sarif, Nira Mawangi   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source