Results 111 to 120 of about 352,293 (253)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Direct instantaneous torque control strategy for vehicle SRM based on improved convergence rate sliding mode control

Scientific Reports
Traditional sliding mode control for switched reluctance motors in direct instantaneous torque control suffers from significant chattering and long response times, which limit its application in new energy vehicle drive systems.
Jingbo Wu, Hongyao Wang, Liuxi Li, Yafeng Yang, Zhijun Guo   +4 more
doaj   +1 more source

Experimental Study on Dry Friction Behavior of AlumiNm Alloy Casing

Shiyou jixie, 2022
In order to study the frictional and wear behavior of alumiNm alloy casing in gas drilling technology, under dry friction conditions, taking 40CrNmo steel as the pin and 7075 alumiNm alloy as the disc, by means of pin-disc wear test system, the effects ...
Xing Xuesong, Zhang Huizeng, Li Juan
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Evaluation of surface response of SiC and fly ash-filled Prosopis juliflora fibre-reinforced epoxy composites under dry sliding wear conditions using Taguchi method

Journal of Engineering and Applied Science
Prosopis juliflora (PJ) fibre-reinforced polymer composites are fabricated with fly ash and SiC as fillers with different weight percentages. Jute layers are also sandwiched for added strength in the structure.
Suresh Thirupathi, Ayyappan Solai, Shenbaga Velu Pitchumani, Venkatachalam Gopalan, Elango Mallichetty   +4 more
doaj   +1 more source

Friction and wear behaviors of biodegradable Mg-6Gd-0.5Zn-0.4Zr alloy under simulated body fluid condition

Journal of Magnesium and Alloys, 2017
The friction and wear behaviors of biodegradable Mg-6Gd-0.5Zn-0.4Zr (wt%, GZ60K) alloy were evaluated under simulated body fluid (SBF) condition using ball-on-disk configuration and compared with those under dry sliding condition.
Jianwei Dai, Xiaobo Zhang, Qiao Yin, Shengnan Ni, Zhixin Ba, Zhangzhong Wang   +5 more
doaj   +1 more source

Studi Eksperimental dan Analisa Laju Keausan Roller pada Sistem Continously Variable Transmission (CVT) dengan Gerakan Reciprocating [PDF]

, 2016
Sistem transmisi otomatis pada motor matik sudah banyak membahas mengenai roller. Seringnya pergantian roller yang diakibatkan aus, bahkan terkadang roller tersebut mengalami kerusakan perlu ditinjau dari kinematika pergerakan dari roller, laju keausan ...
Kaelani, Y. (Yusuf), Putra, J. A. (Johan)   +1 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Surface recrystallization theory of the wear of copper in liquid methane [PDF]

Copper was subjected to sliding against 440C in liquid methane. The normal load range was from 1/4 to 2 kilograms, and the sliding velocity range was from 3.1 to 25 meters per second.
Bill, R. C., Wisander, D. W.
core   +1 more source