Results 91 to 100 of about 352,293 (253)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Optimization of EHA sliding mode controller based on spider wasp algorithm
Zhongguo Jianchuan YanjiuObjectiveThis paper proposes using the Spider Wasp Optimization (SWO) algorithm to achieve precise position control of an electro-hydrostatic actuator (EHA) while reducing the parameter tuning difficulty of the EHA sliding mode controller and improving ...
Weibo LI +4 more
doaj +1 more source
Effect of velocity on roll/slip for low and high load conditions in polymer composite [PDF]
, 2011 In the last decade polymer composites are often used without lubrication on both low and high speed applications. Some of the application areas are marine, automotive and agriculture used as bearings and cams where roll-slip is the dominant mechanism ...
Andó, MátyásUGent80200081473500009143321027C92CA2-F0EE-11E1-A9DE-61C894A0A6B4 +4 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Tribological behaviour of the low and high viscosity peek at various testing scales [PDF]
, 2012 Polyetheretherketone (PEEK) has become most attractive as a sliding bearing material in industrial applications, due to its excellent thermal stability, good friction and wear resistance. These properties promote the material to be used in so called high
De Baets, Patrick +6 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Jixie chuandong, 2010 Belts are widely applied to various machine.Elastic sliding is one of the characteristics of friction belt transmission,and it leads to inexact transmission ratio and transmission efficiency decreased of belt drive system.In order to investigate ...
王旭东, 熊平原
doaj
A New Variable Exponential Power Reaching Law of Complementary Terminal Sliding Mode Control
Complexity, 2020 In this article, a new nonlinear algorithm based on the sliding mode control is developed for the ball and plate control system to improve dynamic response and steady-state tracking accuracy of the control system.
Feng Xu, Na An, Jianlin Mao, Shubo Yang
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source