Results 101 to 110 of about 352,293 (253)

Investigation of Wear Behavior in Ni-Ti-SiC Composites Fabricated via Microwave Sintering [PDF]

Materials Research
The combination of nickel (Ni) and titanium alloy (Ti) with silicon carbide (SiC) reinforcement offers promising avenues for research and applications due to their exceptional resistance to heat, oxidation, and corrosion properties.
P. Hariprasad, K. Kumaresan, Bader Alqahtani, Abdulkarim Alansari   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The motion of a drop in a rigid surface [PDF]

, 1982
The assumptions of a region of slip near a moving contact line (to remove the force singularity) and a constant contact angle are used to obtain the equation for the shape of a thin drop of liquid resting on a rigid plane. Three asymptotic expansions are
Hocking, L. M.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Study on maximum sliding rate of planetary gear train with center distance error and optimization of modification coefficient

Jixie chuandong
ObjectiveAiming at the problems of severe tooth surface wear and gluing failure in the planetary reducers of baling equipment under heavy loads, the maximum sliding rate and its influencing factors in a 3K-I planetary gear train with center distance ...
LI Chuanxiang, CHEN Dong, WANG Zhaoyang, WANG Xiao, XU Huanping   +4 more
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

THE EFFECT OF VARIOUS PARAMETERS ON DRY SLIDING WEAR BEHAVIOR AND SUBSURFACE OF AGED HYBRID METAL MATRIX COMPOSITES USING TAGUCHI TECHNIQUE

Iranian Journal of Materials Science and Engineering, 2017
The effects of applied load, sliding speed and sliding distance on the dry sliding wear behavior of aged Al-SiCp-Gr composites were investigated. The specimen were fabricated by stir-casting technique.
B.M. Viswanatha, M. Prasanna Kumar, S. Basavarajappa, T.S. Kiran   +3 more
doaj  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Dynamic Terminal Sliding Mode Control for an Aerospace Launch Vehicle [PDF]

فصلنامه علوم و فناوری فضایی, 2016
Tracking guidance commands for a time-varying aerospace launch vehicle during the atmospheric flight is considered in this paper. Hence, the dynamic terminal sliding mode control law is constructed for this purpose and dynamic sliding mode control is ...
Ali Reza Alikhani, Seyed Aliakbar Kasaeian   +1 more
doaj