Results 11 to 20 of about 27,932 (217)

LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slug

open access: yesAntioxidants, 2021
LW1497 suppresses the expression of the hypoxia-inducing factor (HIF)-1α inhibiting malate dehydrogenase. Although hypoxia and HIF-1α are known to be important in cancer, LW1497 has not been therapeutically applied to cancer yet.
Hyun Ji Kim   +19 more
doaj   +1 more source

Notch Signaling Pathway Regulates Epithelial-mesenchymal Transition of Osteosarcoma by Activating Slug

open access: yesZhongliu Fangzhi Yanjiu, 2020
Objective To investigate the effect and mechanism of Notch signaling pathway on epithelial-mesenchymal transition (EMT) of osteosarcoma. Methods We used lentivirus transfection technology to transfect osteosarcoma cells, and used si-slug to knock down ...
CHEN Jingteng   +4 more
doaj   +1 more source

Riser slugging - a mathematical model and the practical consequences [PDF]

open access: yesModeling, Identification and Control, 2005
This article presents a novel approach to estimate severe riser slug build up time and consequently the slug period. The slug model is based on a simplified mechanical model.
Svein I. Sagatun
doaj   +1 more source

The Fate of Deroceras reticulatum Following Metaldehyde Poisoning

open access: yesInsects, 2021
The concentration of a pesticide used in agriculture not only has implications for effectiveness of pest control but may also have significant wider environmental consequences.
Amy Campbell, Neil Audsley, Gordon Port
doaj   +1 more source

Co-Occurrence of Domestic Dogs and Gastropod Molluscs in Public Dog-Walking Spaces and Implications for Infection with Angiostrongylus vasorum: A Preliminary Study

open access: yesAnimals, 2021
Angiostrongylusvasorum is a helminth parasite of domestic dogs that is increasing in range and prevalence. Its lifecycle requires terrestrial gastropod mollusc (“gastropod”) intermediate hosts, but research is lacking regarding contact risk in situ.
Bryony A. Tolhurst   +4 more
doaj   +1 more source

Invasion Potential of Ornamental Terrestrial Gastropods in Europe Based on Climate Matching

open access: yesDiversity, 2023
Invasive species are one of the main causes of biodiversity loss worldwide. Pet trade is a well-known pathway for the introduction of non-native species.
Lucie Bohatá, Jiří Patoka
doaj   +1 more source

Experimental and Numerical Study on the Slug Characteristics and Flow-Induced Vibration of a Subsea Rigid M-Shaped Jumper

open access: yesApplied Sciences, 2023
The subsea jumper has become an essential part of subsea production systems as a gas–liquid mixing pipeline connecting the pipeline end manifold (PLEM) to the Christmas tree.
Wenhua Li   +3 more
doaj   +1 more source

An investigation on the mollusc fauna in west and south of Tehran Province, Iran [PDF]

open access: yesیافته‌های نوین در علوم زیستی, 2023
Molluscs are important pests of natural and agricultural ecosystems, by feeding on different parts of leaves, stems, flowers, buds, fruits and roots of different plant hosts, reducing the marketability of annual agricultural products and damage plant ...
Mina Azhary, Elham Ahmadi
doaj  

Slug increases sensitivity to tubulin‐binding agents via the downregulation of βIII and βIVa‐tubulin in lung cancer cells

open access: yesCancer Medicine, 2013
Transcription factor Slug/SNAI2 (snail homolog 2) plays a key role in the induction of the epithelial mesenchymal transition in cancer cells; however, whether the overexpression of Slug mediates the malignant phenotype and alters drug sensitivity in lung
Daisuke Tamura   +18 more
doaj   +1 more source

An experimental investigation of the stochastic nature of slug flow [PDF]

open access: yesE3S Web of Conferences, 2023
Slug flow is widely encountered in oil and gas systems. It has an unsteady hydrodynamic behavior that motivated the development of mechanistic models to better understand and quantify the parameters of the flow. The present work investigated several slug
García César   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy