Results 21 to 30 of about 55,562 (295)
Cancer Biology & Therapy, 2023 As the most common histological subtype of primary lung cancer, lung adenocarcinoma (LUAD) causes enormous cancer deaths worldwide. Radiotherapy has been frequently used in LUAD cases, and radiosensitivity is vital for LUAD therapy.
Chongxin Li +10 more
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Nature Cardiovascular Research, 2022 Atherosclerotic plaques consist mostly of smooth muscle cells (SMCs), and genes that influence SMC phenotype can modulate coronary artery disease (CAD) risk.
Paul P. Cheng +12 more
semanticscholar +1 more source
Molecules, 2020 For hepatic failure, stem cell transplantation has been chosen as an alternative therapy, especially for mesenchymal stem cells (MSCs). The aim of this study was to investigate the effect of eugenol (EUG) on the in vivo antifibrotic activity of adipose ...
Moustafa Fathy +3 more
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Activin A regulates activation of mouse neutrophils by Smad3 signalling [PDF]
Open Biology, 2017 Activin A, a member of the transforming growth factor beta superfamily, acts as a pro-inflammatory factor in acute phase response, and influences the pathological progress of neutrophil-mediated disease.
Yan Qi +5 more
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Investigation of SMAD3 and SMAD4 Genes Expression in CML Patients and K562 Cell Line [PDF]
Armaghane Danesh Bimonthly Journal, 2023 Background & aim: Chronic myeloid leukemia or CML is a clonal myeloproliferative disorder with abnormal Philadelphia chromosome cytogenetic index. One of the important signaling pathways in the process of proliferation and apoptosis of cancer cells and ...
T Mahdloo, HR Godarzi, M Jafarinia
doaj
Frontiers in Oncology, 2021 tRNA derivatives have been identified as a new kind of potential biomarker for cancer. Previous studies have identified that there were 30 differentially expressed tRNAs derivatives in breast cancer tissue with the high-throughput sequencing technique ...
Dongping Mo +5 more
semanticscholar +1 more source
SMAD3 Regulates Gonadal Tumorigenesis [PDF]
Molecular Endocrinology, 2007 Inhibin is a secreted tumor suppressor and an activin antagonist. Inhibin alpha null mice develop gonadal sex cord-stromal tumors with 100% penetrance and die of a cachexia-like syndrome due to increased activin signaling. Because Sma and Mad-related protein (SMAD)2 and SMAD3 transduce activin signals in vitro, we attempted to define the role of SMAD3 ...
Qinglei, Li +4 more
openaire +2 more sources
Comprehensive analysis of m6A methylomes in idiopathic pulmonary arterial hypertension
Epigenetics, 2023 Idiopathic pulmonary arterial hypertension (IPAH) is a serious and fatal disease. Recently, m6A has been reported to play an important role in the lungs of IPAH patients and experimental pulmonary hypertension models. However, the meaning of m6A mRNAs in
Ting Huang +9 more
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Resveratrol inhibits TGF-β1–induced fibrotic effects in human pterygium fibroblasts
Environmental Health and Preventive Medicine, 2023 Background: Resveratrol is a polyphenolic phytoalexin which has the properties of anti-oxidant, anti-inflammatory and anti-fibrotic effects. The aim of this study was to investigate the anti-fibrotic effects of resveratrol in primary human pterygium ...
Jianwu Fan +7 more
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Autoimmunity, 2022 Circular RNA (circRNA) has been confirmed to be the key regulators of diabetic nephropathy (DN) progression. However, the role of circ_0114428 in the DN progression remains unclear. Glomerular mesangial cells (GMCs) were treated with high glucose (HG) to
Bo Li +4 more
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