Results 121 to 130 of about 1,611,169 (342)
Comparison of Super Resolution Reconstruction Acquisition Geometries for Use in Mouse Phenotyping
International Journal of Biomedical Imaging, 2013 3D isotropic imaging at high spatial resolution (30–100 microns) is important for comparing mouse phenotypes. 3D imaging at high spatial resolutions is limited by long acquisition times and is not possible in many in vivo settings.
Niranchana Manivannan +3 more
doaj +1 more source
The future of hybrid imaging—part 3: PET/MR, small-animal imaging and beyond
Insights into Imaging, 2011 Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information.
T. Beyer +3 more
semanticscholar +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Withrow & MacEwen's small animal clinical oncology /
, 2007 Focusing on cancer in dogs and cats, this extensively updated 4th edition provides comprehensive coverage of the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. Ideal for students, practitioners,
Vail, David M., Withrow, Stephen J.
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A digital ultrasonic system for small animal imaging
, 2009 [[abstract]]© 2004 Elsevier-In this paper, a 50 MHz digital ultrasonic imaging system designed for small animals and its applications to mouse embryos and tumors are presented.
Meng-Lin Li; Yen-Fu Chen; Wei-Jung Guan; Pai-Chi Li +1 more
core
In vivo quantitative FRET small animal imaging: Intensity versus lifetime-based FRET. [PDF]
Biophys Rep (N Y), 2023 Smith JT +5 more
europepmc +1 more source
PLoS ONE, 2011 Background Small animal models of human diseases are an indispensable aspect of pre-clinical research. Being dynamic, most pathologies demand extensive longitudinal monitoring to understand disease mechanisms, drug efficacy and side effects.
Deepu R. Pillai +12 more
semanticscholar +1 more source