Results 211 to 220 of about 12,783,707 (261)

Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer. [PDF]

Cancer Discov
Schroeder BA, Mohindroo C, Meinhardt AL, Takahashi N, Zhang Y, Lee MJ, Sahoo S, Donahue RN, Kumar R, Nirula M, Yang Y, Rastogi S, Sato N, Lee S, Tsai YT, Zhuang S, Kazi A, Huang Y, Desai P, Nichols S, Sciuto L, Pinkiert D, Chrisafis G, Greenberg M, Biery DN, Al-Marayaty R, Yang HH, Lee MP, Schultz CW, El Meskini R, Atkinson D, Fousek K, Gulley JL, Schlom J, Sato M, Shrestha RL, Sharma AK, Jolly MK, Palena C, Wakefield LM, Thomas A.   +40 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Novel Compounds as SMARCA2 Inhibitors for Treating Non-small Cell Lung Cancer. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Cardiac Metastasis Mimicking Lateral STEMI in Small-Cell Lung Cancer. [PDF]

JACC Case Rep
Erdoğdu OU, Yılmaz Öztekin GM.
europepmc   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Defining the tumor microenvironment of non-small cell lung cancer. [PDF]

Immunol Cell Biol
Embaye KS, Blick T, Naei VY, O'Byrne K, Hughes BGM, Kulasinghe A.   +5 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Unveiling BRAF Mutations in Non-small Cell Lung Cancer: State of the Art and Future Perspectives. [PDF]

Lung
Colombino M, Paliogiannis P, Palomba G, Pisano M, Casula M, Fois AG, Zinellu A, Palmieri G.   +7 more
europepmc   +1 more source