Results 181 to 190 of about 10,585,232 (232)

Cytological Identification of a Rhabdoid Variant of Pancreatic Neuroendocrine Neoplasm

open access: yesCytopathology, Volume 37, Issue 6, Page 641-647, November 2026.
Intracytoplasmic inclusions observed in rhabdoid‐type neuroendocrine tumours are evident on Giemsa staining and show strong cytokeratin (AE1/AE3) positivity on immunocytochemistry. This report describes the cytological features of a rare rhabdoid variant of pancreatic neuroendocrine neoplasm and highlights the diagnostic challenges associated with this
Miyu Okuda   +4 more
wiley   +1 more source

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma

open access: yesHistopathology, Volume 89, Issue 5, Page 779-785, November 2026.
Frequently positive TROP2 IHC suggests that TROP2 antibody‐drug conjugates may be potential treatments for LCNEC. Introduction TROP2 antibody‐drug conjugates have shown promising anti‐tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and ...
Michael Minkley   +6 more
wiley   +1 more source

Characterizing bone metastases and skeletal‐related events in patients with well‐differentiated neuroendocrine neoplasms utilizing 68Gallium‐DOTATATE positron emission tomography

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract Tumors of neuroendocrine origin are a heterogenous group of related neoplasms which can arise from anywhere in the body. Neuroendocrine neoplasms (NENs) are categorized by site of origin, differentiation status and grade (Ki‐67 expression and/or mitotic rate), with significant prognostic variability accordingly. Historically, the prevalence of
Tucker W. Coston   +13 more
wiley   +1 more source

Primary Hepatic Neuroendocrine Neoplasms: Systematic Review and Expert Pathologist Reappraisal Using the WHO 6th Edition Framework

open access: yesLiver International, Volume 46, Issue 11, November 2026.
ABSTRACT Primary hepatic neuroendocrine neoplasms (PHNENs) are exceedingly rare. Published evidence often lacks adequate clinicopathological support for a primary hepatic origin and uses inconsistent historical terminology. Previous reviews have pooled well‐differentiated neuroendocrine tumours (NETs), poorly differentiated neuroendocrine carcinomas ...
Marcello Maestri   +6 more
wiley   +1 more source

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