Results 201 to 210 of about 352,358 (326)

Cell penetrating peptide-functionalized small interfering RNA nanoparticles knock down HER expression in breast cancer cells. [PDF]

J Pharmacol Exp Ther
Dissanayake R, Mishra VK, Ahmed M.
europepmc   +1 more source

Inclisiran-Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9. [PDF]

Pharmaceutics, 2023
Wołowiec Ł, Osiak J, Wołowiec A, Wijata A, Grześk E, Kozakiewicz M, Banach J, Nowaczyk A, Nowaczyk J, Grześk G.   +9 more
europepmc   +1 more source

Design, synthesis and evaluation of novel, branched trident small interfering RNA nanostructures for sequence-specific RNAi activity

, 2019
Akash Chandela, Yoshihito Ueno
openalex   +2 more sources

Small interfering RNA [PDF]

, 2019
openaire   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Editorial expression of concern (EEoC): small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. [PDF]

BMC Cancer
Zhou W, Hu J, Tang H, Wang D, Huang X, He C, Zhu H.   +6 more
europepmc   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Preclinical safety and bleeding evaluation in swine for a small interfering RNA-lipid nanoparticle that prevents excess fibrinogen synthesis. [PDF]

J Thromb Haemost
Seadler MS, Ferraresso F, Turner HM, Ketelboeter LM, Zhang Y, Badior K, Hayssen WG, Chen T, Haugen AL, Cau MF, Robertson M, Skaer C, Bansal M, Murphy PB, de Moya M, Dyer MR, Kastrup CJ.   +16 more
europepmc   +1 more source

Emergence of Small Interfering RNA-Based Gene Drugs for Various Diseases. [PDF]

ACS Omega, 2023
Kurakula H, Vaishnavi S, Sharif MY, Ellipilli S.   +3 more
europepmc   +1 more source

Phytophthora Have Distinct Endogenous Small RNA Populations That Include Short Interfering and microRNAs

, 2013
Noah Fahlgren, Stephanie R. Bollmann, Kristin D. Kasschau, Josh T. Cuperus, Caroline M. Press, Christopher M. Sullivan, Elisabeth J. Chapman, J. Steen Hoyer, Kerrigan B. Gilbert, Niklaus J. Grünwald, James C. Carrington   +10 more
openalex   +2 more sources