Results 221 to 230 of about 625,167 (353)

Use of adeno-associated viral vector for delivery of small interfering RNA

, 2003
Raghuvir Singh Tomar, Hittu Matta, Preet M. Chaudhary   +2 more
openalex   +1 more source

ROS‐Driven Nanoventilator for MRSA‐Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti‐Inflammation and Immunomodulation

Advanced Science, EarlyView.
A ROS‐driven in situ oxygen supply nanoventilator based on enzyme nanocapsule can convert ROS into O2 through enzyme cascade reaction between SOD and CAT to relieve lung hypoxia, and kill MRSA by releasing vancomycin, which effectively reduces HIF‐1α expression and balances pro‐inflammatory/anti‐inflammatory macrophages ratio, thereby reducing the ...
Zheng Luo, Qi Wang, Xiaotong Fan, Xue Qi Koh, Xian Jun Loh, Caisheng Wu, Zibiao Li, Yun‐Long Wu   +7 more
wiley   +1 more source

Inhibition of Glucocorticoid-induced Apoptosis by Targeting the Major Splice Variants of BIM mRNA with Small Interfering RNA and Short Hairpin RNA [PDF]

, 2004
Marc Abrams, Noreen M. Robertson, Kyonggeun Yoon, Eric Wickstrom   +3 more
openalex   +1 more source

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

Advanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang, Jane Frederick, Karla Isabel Medina, Elizabeth Thomas Bartom, Luay Matthew Almassalha, Yaqi Zhang, Greta Wodarcyk, Hao Huang, I Chae Ye, Ruyi Gong, Cody Levi Dunton, Alex Duval, Paola Carrillo Gonzalez, Joshua Pritchard, John Carinato, Iuliia Topchu, Junzui Li, Zhe Ji, Mazhar Adli, Vadim Backman, Daniela Matei   +20 more
wiley   +1 more source

Small Interfering RNA Therapy for the Management and Prevention of Hypertension. [PDF]

Curr Hypertens Rep
Ren L, Danser AHJ.
europepmc   +1 more source

Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α [PDF]

, 2004
Xiuwu Zhang, Takashi Kon, Wang He, Fang Li, Qian Huang, Zahid N. Rabbani, John P. Kirkpatrick, Željko Vujašković, Mark W. Dewhirst, Chuan‐Yuan Li   +9 more
openalex   +1 more source

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

Advanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding, Siwei Mao, Han Wu, Sijia Fang, Ni Zhen, Tianshu Chen, Jiabei Zhu, Xiaochen Tang, Xiaoyang Wang, Fenyong Sun, Guoqing Zhu, Qiuhui Pan, Ji Ma   +12 more
wiley   +1 more source

Nanoparticles-Based Strategies to Improve the Delivery of Therapeutic Small Interfering RNA in Precision Oncology. [PDF]

Pharmaceutics, 2022
Huang J, Xiao K.
europepmc   +1 more source

Small interfering RNA production by enzymatic engineering of DNA (SPEED) [PDF]

, 2004
Biao Luo, Amanda Heard, Harvey F. Lodish
openalex   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source