Results 221 to 230 of about 352,358 (326)

Multichannel 3D-Printed Bioactive Scaffold Combined with Small Interfering RNA Delivery to Promote Neurological Recovery after Spinal Cord Injury. [PDF]

open access: yesResearch (Wash D C)
Ye J   +12 more
europepmc   +1 more source

Antisense Oligonucleotides and Small Interfering RNA for the Treatment of Dyslipidemias. [PDF]

open access: yesJ Clin Med, 2022
Gareri C   +5 more
europepmc   +1 more source

Selective silencing of DNA topoisomerase IIβ in human mesenchymal stem cells by siRNAs (small interfering RNAs) [PDF]

open access: hybrid, 2011
Nebiyyeh Kamaci   +5 more
openalex   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Small Interfering RNA–Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture [PDF]

open access: hybrid, 2008
Lucy Marzban   +7 more
openalex   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

open access: yesAdvanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha   +7 more
wiley   +1 more source

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

open access: yesAdvanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim   +12 more
wiley   +1 more source

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