Results 251 to 260 of about 336,966 (279)

Dual Foreign Body Response Mitigation Strategies for Implantable Glucose Sensors

Advanced Sensor Research, EarlyView.
The foreign body response negatively impacts the analytical lifetime of implantable glucose sensors due to a heightened immune response and deposition of collagen. While nitric oxide release has shown promise as a foreign body response mitigation strategy, improvement is limited by the duration of release.
Taron M. Bradshaw, Mikaylin E. Nogler, Matthew F. Warchol, Micah L. Willis, Alejandro R. Walker, Robert Maile, Shannon M. Wallet, Elizabeth P. Merricks, Timothy C. Nichols, Mark H. Schoenfisch   +9 more
wiley   +1 more source

Label‐Free, Sensitive, and Direct Detection of Cardiac Troponin Biomarkers Using Frequency‐Locked Microring Resonators

Advanced Sensor Research, EarlyView.
A deployable, chip‐integrated approach to the detection of heart attack biomarkers is demonstrated using silicon photonic microring resonators combined with microfluidics. By applying the Pound–Drever–Hall frequency locking technique, sensor signals are measured with improved signal‐to‐noise ratio, applying this to real‐time, selective readouts.
Evan Diamandikos, Tetsuya Shimogaki, Crispin Szydzik, Peter Thurgood, Luke H. Broadley, Sonya Palmer, Guanghui Ren, Thach G. Nguyen, Cesar S. Huertas, Arnan Mitchell   +9 more
wiley   +1 more source

Beyond Plasmonics: Atomic‐Scale SERS Platforms for Plasmon‐Free Photocatalysis Monitoring via Charge Transfer Mechanisms

Advanced Sensor Research, EarlyView.
This perspective discusses the charge transfer mechanism in single‐atom/small‐cluster SERS systems supported by semiconducting and metallic substrates. Integrating single‐atom/small‐cluster SERS with photocatalytic processes offers unprecedented opportunities for real‐time plasmon‐free reaction monitoring.
Ruinan Wang, Yunjia Wei, Guoqun Li, Shuying Chen, Jie Lin, Qi Hao, Xingce Fan, Teng Qiu   +7 more
wiley   +1 more source

Plant Virus-Derived Small Interfering RNAs Originate Predominantly from Highly Structured Single-Stranded Viral RNAs

, 2005
Attila Molnár, Tibor Csorba, Lóránt Lakatos, Éva Várallyay, Christophe Lacomme, József Burgyán   +5 more
openalex   +1 more source

Determination of Optimum Ratio of Cationic Polymers and Small Interfering RNA with Agarose Gel Retardation Assay.

Methods Mol Biol, 2022
Aydin O, Kanarya D, Yilmaz U, Tunç CÜ.
europepmc   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

Genomic Analysis of Anti-Hepatitis B Virus (HBV) Activity by Small Interfering RNA and Lamivudine in Stable HBV-Producing Cells

, 2005
Yong Guo, Hongyan Guo, Liang Zhang, Xie Hong-ying, Xin Zhao, Fangxun Wang, Ze Li, Yahui Wang, Shiliang Ma, Jiaping Tao, Weixing Wang, Yuxiang Zhou, Weiping Yang, Jing Cheng   +13 more
openalex   +1 more source

Perivascular CLICK-gelatin delivery of thrombospondin-2 small interfering RNA decreases development of intimal hyperplasia after arterial injury. [PDF]

FASEB J
Mota L, Zhu M, Li J, Contreras M, Aridi T, Tomeo JN, Stafford A, Mooney DJ, Pradhan-Nabzdyk L, Ferran C, LoGerfo FW, Liang P.   +11 more
europepmc   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source