Results 81 to 90 of about 787,224 (277)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
AnimalsAtherosclerosis is highly prevalent among captive psittacine populations and is a frequent cause of veterinary consultations. Ante-mortem diagnosis remains challenging, but the serum lipoprotein analysis has been suggested as a useful tool for ...
Matthias Janeczek +5 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2018 This study determines the presence of R. tanezumi from in Nepal using morphological and molecular analyses. Morphologically, it is indistinguishable with R. rattus owing to similar fur colour and morphometric data.
Pradeep Adhikari +8 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Hystrix, the Italian Journal of Mammalogy, 1997 <strong>Abstract</strong> This paper points out the relationships occurring between small mammal populations studied in some areas of the central-Western italian Alpine Arch, and some environmental parameters that characterize the Alpine ...
Barbara Chiarenzi +2 more
doaj +1 more source
Geographic Distribution of Siphonaptera Collected From Small Mammals on Lake Michigan Islands [PDF]
, 2017 The distribution of ten flea species collected from five small mammal host species on 13 Lake Michigan islands is described. Four new eastern and southern records for Hystrichopsylla dippiei Rothschild are given.
Scharf, William C
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
To respond or not to respond? Natural variation of root architectural responses to nutrient signals [PDF]
, 2017 The amino acid glutamate (Glu) acts as a fast excitatory neurotransmitter in mammals. Its importance in plant signalling was recognized with the discovery of channel proteins similar to mammalian Glu receptors, as well as distinct changes in root-system ...
Amtmann, Anna, Shahzad, Zaigham
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A case study of critical points for the entry and spread of Salmonella Infantis in a broiler farm
Irish Veterinary JournalSalmonella Infantis is a zoonotic pathogen that frequently persists in broiler production systems, posing a risk to food safety and animal health. Understanding its entry and spread in these systems can inform control measures and reduce contamination. A
Bojan Papić +5 more
doaj +1 more source