Results 201 to 210 of about 194,605 (341)
Advanced Healthcare Materials, EarlyView.A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin +15 more
wiley +1 more source
Small Molecule Inhibitors of Mucin-Type O-Linked Glycosylation from a Uridine-Based Library [PDF]
, 2004 Howard C. Hang +6 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Gelatin methacryloyl (GelMA) granular hydrogel scaffolds (GHS) are fabricated using a generalized two‐step photocrosslinking approach to yield stable (non‐dissolving) microgels suitable for in situ covalent assembly under physiological conditions. A phase diagram is developed to define the interplay between individual microgel stability and scaffold ...
Yuanhui Xiang +4 more
wiley +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Porosity governs transport mechanics in hydrogels, yet characterization in its native state remains challenging. This work harnesses particle tracking to uncover three‐dimensional pore geometric features in polyethylene glycol hydrogels. Measurements in the native state reveal pores characteristics are comparable to those obtained by cryogenic scanning
M. A. Kristine Tolentino +5 more
wiley +1 more source
Reporting data from high-throughput screening of small-molecule libraries [PDF]
, 2007 James Inglese +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng +5 more
wiley +1 more source
Assessing the Robustness and Scalability of Machine Learning Methods to Accelerate Ultralarge High-Throughput Docking Campaigns. [PDF]
ACS OmegaDi Filippo JI, Rómoli S, Cavasotto CN.
europepmc +1 more source
High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries. [PDF]
J Biomol Screen, 2012 Nelersa CM +8 more
europepmc +1 more source
Evaluation of a chemical library of small-molecule Dishevelled antagonists that suppress tumor growth by down-regulating T-cell factor–mediated transcription [PDF]
, 2008 Liang You +4 more
openalex +1 more source