Results 121 to 130 of about 202,981 (234)

Nuclear Autoantigenic Sperm Protein Promotes Cardiac Regeneration and Repair Through Activating the PDGFRB/AKT Pathway

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
This study revealed an important role of NASP in promoting cardiomyocytes proliferation and cardiac regeneration. In this study, we found that NASP was downregulated in postnatal mice myocardium. Cardiac‐specific overexpression of NASP promoted regenerative repair in adult mice post‐MI through the PDGFRB/AKT pathway. ABSTRACT Myocardial Infarction (MI)
Hao Wang, Di Zhao, Tongtong Yang, Wenjing Wang, Liuhua Zhou, Jiateng Sun, Liu Liu, Lingfeng Gu, Yulin Bao, Liansheng Wang, Qiming Wang   +10 more
wiley   +1 more source

Intron Editing Reveals SNORD-Dependent Maturation of the Small Nucleolar RNA Host Gene GAS5 in Human Cells. [PDF]

Int J Mol Sci, 2023
Matveeva A, Vinogradov D, Zhuravlev E, Semenov D, Vlassov V, Stepanov G.   +5 more
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, Volume 19, Issue 8, Page 2174-2195, August 2025.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Fibrillarin-associated Box C/D Small Nucleolar RNAs inTrypanosoma brucei [PDF]

, 2000
David A. Dunbar, Steven Wormsley, Todd M. Lowe, Susan J. Baserga   +3 more
openalex   +1 more source

Unveiling Small Non‐Coding RNA Dynamics During Recombinant Adeno‐Associated Virus Production

Biotechnology Journal, Volume 20, Issue 8, August 2025.
Graphical Abstract and Lay Summary In this study, we explored the largely underexamined role of non‐coding RNAs in recombinant adeno‐associated virus (rAAV) production. Using a time‐course, multi‐layered analytical approach in HEK293F cells, we identified 142 differentially expressed microRNAs and five snoRNAs involved in key cellular processes ...
Madina Burkhart, Katrin Langenbach, Karlheinz Holzmann, Nadine Hornung, Jamie‐Ann Baiz, Kerstin Otte   +5 more
wiley   +1 more source

The association of UBAP2L and G3BP1 mediated by small nucleolar RNA is essential for stress granule formation. [PDF]

Commun Biol, 2023
Asano-Inami E, Yokoi A, Sugiyama M, Hyodo T, Hamaguchi T, Kajiyama H.   +5 more
europepmc   +1 more source

A Novel Brain-specific Box C/D Small Nucleolar RNA Processed from Tandemly Repeated Introns of a Noncoding RNA Gene in Rats [PDF]

, 2001
Jérôme Cavaillé, Patrice Vitali, Eugénia Basyuk, Alexander Hüttenhofer, Jean‐Pierre Bachellerie   +4 more
openalex   +1 more source

A robust machine learning model based on ribosomal‐subunit‐derived piRNAs for diagnostic potential of nonsmall cell lung cancer across multicentre, large‐scale of sequencing data

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
NSCLC lacks robust noninvasive biomarkers. We curated 2050 invasive and noninvasive samples, integrating public and in‐house plasma/exosome data. A machine learning model using five tumour‐specific piRNA signatures formed the piRNA‐Based Tumour Probability Index (pi‐TPI), achieving AUC values up to .96, demonstrating strong potential for NSCLC ...
Zitong Gao, Masaki Nasu, Gehan Devendra, Ayman A. Abdul‐Ghani, Anthony J. Herrera, Jeffrey A. Borgia, Christopher W. Seder, Donna Lee Kuehu, Zhuokun Feng, Yu Chen, Ting Gong, Zao Zhang, Owen Chan, Hua Yang, Jianhua Yu, Yuanyuan Fu, Lang Wu, Youping Deng   +17 more
wiley   +1 more source

Circulating U13 Small Nucleolar RNA as a Potential Biomarker in Huntington's Disease: A Pilot Study. [PDF]

Int J Mol Sci, 2022
Romano S, Romano C, Peconi M, Fiore A, Bellucci G, Morena E, Troili F, Cipollini V, Annibali V, Giglio S, Mechelli R, Ferraldeschi M, Veneziano L, Mantuano E, Sani G, Vecchione A, Umeton R, Giubilei F, Salvetti M, Corbo RM, Scarabino D, Ristori G.   +21 more
europepmc   +1 more source

Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain [PDF]

, 2001
Céline Verheggen, John Mouaikel, Marie Françoise Thiry, Jean‐Marie Blanchard, David Tollervey, Rémy Bordonné, Denis L. J. Lafontaine, Édouard Bertrand   +7 more
openalex   +1 more source