Results 11 to 20 of about 442,180 (329)
Small Nucleolar Derived RNAs as Regulators of Human Cancer
Biomedicines, 2022 In the past decade, RNA fragments derived from full-length small nucleolar RNAs (snoRNAs) have been shown to be specifically excised and functional.
Alexander Bishop Coley +3 more
doaj +3 more sources
Small Nucleolar (Sno)RNA: Therapy Lays in Translation
Non-Coding RNA, 2023 The ribosome is one of the largest complexes in the cell. Adding to its complexity are more than 200 RNA modification sites present on ribosomal RNAs (rRNAs) in a single human ribosome.
Ofri Rabany, Daphna Nachmani
doaj +3 more sources
A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS [PDF]
eLife, 2019 Small nucleolar RNAs (snoRNAs) are a diverse group of non-coding RNAs that direct chemical modifications at specific residues on other RNA molecules, primarily on ribosomal RNA (rRNA).
M. McMahon +15 more
semanticscholar +4 more sources
ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs [PDF]
, 2005 Posttranscriptional, site-specific adenosine to inosine (A-to-I) base conversions, designated as RNA editing, play significant roles in generating diversity of gene expression.
Patrice Vitali +6 more
openalex +11 more sources
Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster [PDF]
Nature Genetics, 2008 Trilochan Sahoo +8 more
openalex +2 more sources
Mammalian small nucleolar RNAs are mobile genetic elements [PDF]
PLoS Genetics, 2005 Small nucleolar RNAs (snoRNAs) of the H/ACA box and C/D box categories guide the pseudouridylation and the 2'-O-ribose methylation of ribosomal RNAs by forming short duplexes with their target. Similarly, small Cajal body-specific RNAs (scaRNAs) guide modifications of spliceosomal RNAs. The vast majority of vertebrate sno/scaRNAs are located in introns
Michel Weber
openalex +7 more sources
The circadian dynamics of small nucleolar RNA in the mouse liver [PDF]
Journal of The Royal Society Interface, 2017 AbstractThe circadian regulation of gene expression allows plants and animals to anticipate predictable environmental changes. While the influence of the circadian clock has recently been shown to extend to ribosome biogenesis, the dynamics and regulation of the many small nucleolar RNA that are required in pre-ribosomal RNA folding and modification ...
Stuart Aitken, Colin A. Semple
+8 more sources
Commuting to Work: Nucleolar Long Non-Coding RNA Control Ribosome Biogenesis from Near and Far
Non-Coding RNA, 2021 Gene expression is an essential process for cellular growth, proliferation, and differentiation. The transcription of protein-coding genes and non-coding loci depends on RNA polymerases.
Victoria Mamontova +3 more
doaj +1 more source
IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2021 The small nucleolar RNA host genes (SNHGs) belong to the long non‐coding RNAs and are reported to be able to influence all three levels of cellular information‐bearing molecules, that is, DNA, RNA, and proteins, resulting in the generation of complex ...
A. Biagioni +9 more
semanticscholar +1 more source
Small Nucleolar RNAs in Pseudoexfoliation Glaucoma
Cells, 2022 Small nucleolar RNAs (snoRNAs) are small non-coding regulatory RNAs that have been investigated extensively in recent years. However, the relationship between snoRNA and glaucoma is still unknown. This study aims to analyze the levels of snoRNA expression in the aqueous humor (AH) of patients with pseudoexfoliation glaucoma (PEXG) compared to a control
Karolina Gasińska +5 more
openaire +3 more sources